无创机械通气治疗慢性阻塞性肺疾病合并呼吸衰竭的临床观察

目的：探讨无创机械通气治疗慢性阻塞肺疾病（COPD）合并慢性呼吸衰竭的临床疗效。方法：选取49例COPD合并呼吸衰竭患者,随机分对照组（24例）和治疗组（25例）,对照组采用常规治疗,治疗组在常规治疗基础上进行口鼻面罩双水平气道正压无创通气治疗,观察并比较两组患者治疗前、治疗4h后、治疗3d后呼吸、心率、动脉血气变化情况及临床疗效。结果：对照组有效率为45.83%,治疗组有效率为76.00%,两组有效率比较,差异有统计学意义（P〈0.05）;治疗组pH、PaO2、PaCO2、呼吸、心率等指标的改善明显优于对照组（P〈0.05）。结论：BiPAP呼吸机经口鼻面罩无创通气治疗COPD合并呼吸衰竭效果显著。

Clinical observation of non-invasive bilevel continuous airway pressure ventilation on chronic obstructive pulmonary disease complicated with respiratory failure

Objective：To discuss the clinical effect of non-invasive mechanical ventilation for the treatment of chronic obstructive pulmonary disease（COPD） associated with chronic respiratory failure.Methods：49 cases of COPD patients complicated with respiratory failure were randomly divided into two groups：non-invasive mechanic ventilation treatment group（25 cases） and control group（24 cases）.The routine treatment was used in control group,and the non-invasive mechanical ventilation was used in treatment group based on the routine treatment.The breathing,heart rate,blood gas and clinical effectiveness of the two groups of patients were observed and compared before treatment,after 4 hours and 3 days of therapy.Results：The total effective rate of control group was 45.83%,while the treatment group achieved an effective rate of 76.00%,and the effective rate of treatment groups was significant higher compared with cortrol group（P0.05）,the blood pH,PaO2,PaCO2,breathing and heart rate of the treatment group improved significant（P0.05）.Conclusion：Non-invasive ventilation in the treatment of COPD patients with respiratory failure has a significant curative effect.