| Abstract: | Changes in the systemic circulation, the blood flow in the kidney and limb, and certain endocrine and metabolic indices were studied in 24 dogs subjected to circulatory arrest of maximal severity for 17 min in the course of 9 h of the postresuscitation period. Relative compensation and normalization of certain functions and metabolic indices during the first hour after resuscitation were subsequently followed by a new wave of disorders which developed at different times, unequally, and gradually in the body as a whole and in individual peripheral tissues. Disturbances of the peripheral circulation and central hemodynamics were shown to be among the leading pathological manifestations of postresuscitation sickness.Research Laboratory of General Resuscitation, Academy of Medical Sciences of the USSR, Moscow. (Presented by Academician of the Academy of Medical Sciences of the USSR V. A. Negovskii.) Translated from Byulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 87, No. 1, pp. 3–6, January, 1979. |
