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Preoperative Arterial Embolization for Heterotopic Ossification of the Hip
Institution:1. Department of Diagnostic and Interventional Radiology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy;2. Department of Orthopaedic Oncology, IRCCS Istituto Ortopedico Rizzoli, Bologna, Italy;1. Department of Radiology, Section of Interventional Radiology, Northwestern Memorial Hospital, Chicago, Illinois;2. Department of Medicine, Section of Gastroenterology, Northwestern Memorial Hospital, Chicago, Illinois;3. Department of Surgery, Northwestern Memorial Hospital, Chicago, Illinois;1. Long Island Jewish Medical Center, Northwell Health System, Queens, New York;2. New York Institute of Technology College of Osteopathic Medicine, Old Westbury, New York;3. Zucker School of Medicine at Hofstra University/Northwell Health System, Hempstead, New York;4. Icahn School of Medicine at Mount Sinai Hospital, New York, New York;1. Interventional Radiology, Louisiana State University Health Sciences Center, New Orleans, Louisiana;2. Vascular and Interventional Specialists, Charlotte Radiology, Charlotte, North Carolina;3. Interventional Radiology, Northwestern Medicine, Palos Health, Palos Heights, Illinois;4. Los Angeles Imaging and Interventional Consultants, PIH Health, Whittier, California;5. Gastroenterology and Hepatology, Atrium Health, Charlotte, North Carolina;6. Division of Hepatobiliary and Pancreas Surgery, Atrium Health, Charlotte, North Carolina;1. Division of Vascular and Interventional Radiology, Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin;2. Department of Radiology, Medical College of Wisconsin, Milwaukee, Wisconsin;3. Department of Pathobiology, University of Pennsylvania School of Veterinary Medicine, Philadelphia, Pennsylvania;4. Division of Vascular and Interventional Radiology, Department of Radiology, University of California San Diego, La Jolla, California
Abstract:PurposeTo investigate the efficacy and safety of preoperative arterial embolization for neurogenic heterotopic ossification (NHO) of the hip.Materials and MethodsThis single-center retrospective study reviewed outcomes in 16 consecutive patients who had surgical resection of NHO of the hip: 8 of whom underwent preoperative arterial embolization and 8 of whom did not. Both patient cohorts had similar baseline characteristics. A mean of 2.62 ± 1.9 arteries per patient, including the gluteal, lateral circumflex femoral, and deep circumflex iliac branches, were embolized using an n-butyl cyanoacrylate (NBCA)–ethiodized oil mixture. Data from both cohorts regarding intraoperative blood loss, volume of blood transfused, complications, and duration of hospitalization were compared.ResultsA mean of 2.6 ± 1.9 arteries were embolized with NBCA–ethiodized oil, mainly the gluteal arteries, lateral circumflex femoral artery, and deep circumflex iliac artery. In the embolization group, mean intraoperative blood loss was 875 mL ± 320, mean number of units of blood used was 0.5 ± 0.7, and mean number of days of hospitalization was 6.4 days ± 1.6. In the control group, mean intraoperative blood loss was 1,350 mL ± 120, mean number of units of blood used was 2 ± 1.1, and average number of days of hospitalization was 11.5 days ± 1.4. The embolization group had a mean reduction in blood loss of 40.7% (P = 0.035), reduction in units of blood administered of 75% (P = 0.021), and reduction in days of hospitalization of 44.7% (P = 0.014). No procedural complications were recorded.ConclusionsPreoperative arterial embolization is effective and safe in reducing intraoperative blood loss, number of hospitalization days, and need for blood transfusions in surgical resection of NHO of the hip.
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