Orofacial anatomical and occlusal changes in patients with sickle cell disease in Kuwait |
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Affiliation: | 1. Department of Diagnostic Sciences, College of Dentistry, Kuwait University, P.O.Box 24923, Safat 13110, Kuwait;2. Department of Hematology, Amiri Hospital, Ministry of Health, 25, Kuwait City, Kuwait |
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Abstract: | ObjectiveSickle cell disease (SCD) is the most common hemoglobinopathy where morphologic changes to red blood cells affect the development of hard and soft tissues. The purpose of this study is to identify the craniofacial characteristics and maxillomandibular relationship in SCD patients and compare with unaffected subjects, through cephalometric radiographic assessment.Materials and MethodsThe study included 44 Kuwaiti SCD patients (20 female, 24 male) as well as 44 age and gender matched controls. Digital lateral cephalometric, radiographs were recorded. SNA and ANB angles were measured and compared.ResultsThe mean SNA angle was found to be higher among the SCD cases (83.00 ± 3.22) than in controls (81.78 ± 4.58), but the difference was not statistically significant, (p = 0.146). The mean ANB angle in SCD cases (5.27 ± 2.36) was significantly higher, than that in controls (3.97 ± 2.23). The difference in means was statistically significant, (p = 0.01). Almost 50% of the SCD patients had class II malocclusion and 61.5% of the patients had prognathic maxilla.ConclusionsPatients with SCD in Kuwait exhibited characteristics of skeletal class II pattern malocclusion. They also showed evidence of compensatory maxillary expansion. |
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Keywords: | Sickle cell anemia Sickle cell disease Cephalometric analysis SNA angle ANB angle Malocclusion |
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