Influence of the gut microbiota on satiety signaling |
| |
| Institution: | 1. Department of Human Biology, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre+, Maastricht, The Netherlands;2. Centre for Healthy Eating and Food Innovation, Maastricht University, Campus Venlo, Venlo, The Netherlands;3. Department of Nutrition and Movement Sciences, NUTRIM School of Nutrition and Translational Research in Metabolism, Maastricht University Medical Centre, Maastricht, The Netherlands;1. Department of Physiology and Pharmacology, Karolinska Institutet, 171 77 Solna, Sweden;2. The Swedish School of Sport and Health Sciences, 114 33 Stockholm, Sweden;1. Department of Internal Medicine, CARIM School for Cardiovascular Diseases, MUMC+, Maastricht, The Netherlands;2. Karolinska Institutet, Stockholm, Sweden;1. State Key Laboratory of Genetic Engineering and School of Life Sciences, Fudan University, Shanghai, 200438, China;1. Hebrew University Medical School, Jerusalem 91120, Israel;1. Division of Genetics, Department of Medicine, Brigham and Women’s Hospital, Harvard Medical School, Boston, MA 02115, USA;2. Department of Neurology and Neurosurgery, McGill University, Montreal, Quebec, QC H3A 2B4, Canada;3. Metabolic Disorders and Complications Program, and Brain Repair and Integrative Neuroscience Program, Research Institute of the McGill University Health Centre, Montreal, Quebec, QC H4A 3J1, Canada;1. Department of Medicine, University of Adelaide, Adelaide, South Australia, Australia;2. Endocrine and Metabolic Unit, Royal Adelaide Hospital, Adelaide, South Australia, Australia;3. Department of Endocrine and Diabetes, The Queen Elizabeth Hospital, Woodville South, South Australia, Australia;4. Department of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden;5. Department of Endocrinology, Karolinska University Hospital, Stockholm, Sweden |
| |
| Abstract: | Recent studies show a link between the gut microbiota and the regulation of satiety and energy intake, processes that contribute to the development and pathophysiology of metabolic diseases. However, this link is predominantly established in animal and in vitro studies, whereas human intervention studies are scarce. In this review we focus on recent evidence linking satiety and the gut microbiome, with specific emphasis on gut microbial short-chain fatty acids (SCFAs). Based on a systematic search we provide an overview of human studies linking the intake of prebiotics with gut microbial alterations and satiety signaling. Our outcomes highlight the importance of in-depth examination of the gut microbiota in relation to satiety and provide insights into recent and future studies in this field. |
| |
| Keywords: | |
| 本文献已被 ScienceDirect 等数据库收录！ |
|
