刺五加叶的药理作用研究进展

刺五加为临床常用药材,含有皂苷、黄酮、多糖、酚酸等丰富的化学成分,并具有保护心脑血管、抗肿瘤、抗炎、抗氧化、降糖等广泛的药理作用。临床常用部位为根及根茎部分,但由于资源的不可再生性,对可再生性刺五加叶的研究具有重要的意义。在查阅文献的基础上,本文对近年来国内外有关于刺五加叶的药理作用、作用机制及药效物质基础进行了详细的总结概括,发现叶的药理作用研究主要集中在皂苷类,对于其他化学成分研究报道较少;并且刺五加叶能否代替刺五加根及根茎应用于临床,质量标准如何建立,这些问题局限了刺五加叶资源的应用。为了更加全面、科学的开发及利用刺五加叶资源,还有待于进一步的研究。

Research Progress on Pharmacological Effects of Leaves of Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis

Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis is a frequently used herb, which contain saponins, flavonoids, polysaccharides, phenolic acids and other chemical components, and protective cardiovascular,antitumor, anti-inflammatory, antioxidant, blood sugar, such as a wide range of pharmacological effects. Clinical commonly used parts for root and rhizome part, but as a result of resource irrefragable, studying the reproducibility of Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis leaf has the vital significance. On the basis of literature review,this paper about the pharmacological action, mechanism of action and therapeutic effects of material basis of Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis at home and abroad in recent years leaf were summarized,finding leaves of pharmacological effect research main concentrated in saponins, but other chemical components research reported less,and Acanthopanacis Senticosi Radix et Rhizoma Seu Caulis leaf can instead of acanthopanax root and rhizome applied to clinical, how to establish quality standards, these problems limited the application of acanthopanax leaf resources. In order to more comprehensive and scientific development and utilization of acanthopanax leaf resources, has yet to be further research.