毛酸浆的化学成分研究

对毛酸浆的干燥宿萼95%乙醇提取物的二氯甲烷部分进行化学成分的研究。利用正相硅胶柱色谱及反相制备高效液相色谱等方法分离纯化,得到10个化合物,通过质谱、一维及二维核磁共振波谱等手段对这些化合物的化学结构进行了鉴定,分别为5-O-(E-feruloyl)blumenol(1),异香草醛(2),反式对羟基肉桂酸乙酯(3),对羟基苯甲醛(4),对甲苯酚(5),反式肉桂酸甲酯(6),7,3',4'-三甲氧基槲皮素(7),5,3', 5'-三羟基-3,7,4'-三甲氧基黄酮(8),danielone(9),5,5'-二异丁氧基-2,2'-联呋喃(10),其中化合物1为新化合物,化合物7~10为首次从该属植物中分离得到。

Chemical constituents of Physalis pubescens

Chemical constituents of 95% ethanol extract of the dried persistent calyx of Physalis pubescens were investigated. By chromatography on a silica gel column and reverse-phase preparative HPLC, 10 compounds were isolated from the dichloromethane fraction. Based on the MS and 1D/2D NMR data, these compounds were identified as 5-O-(E-feruloyl)blumenol(1), isovanillin(2),(E)-ethyl 3-(4-hydroxyphenyl)acrylate(3), 4-hydroxybenzaldehyde(4), 4-methylphenol(5),(E)-methyl cinnamate(6), 7,3',4'-trimethoxyquercetin(7), 5,3', 5'-trihydroxy-3,7,4'-trimethoxyflavone(8), danielone(9), and 5,5'-diisobutoxy-2,2'-bifuran(10). Compound 1 was a new one, while compounds 7-10 were obtained from the genus Physalis for the first time.