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Expanding Awareness of the Distribution and Biologic Potential of Ectomesenchymal Chondromyxoid Tumor
Authors:Justin Bubola  Klieb Hagen  Nick Blanas  Ilan Weinreb  Brendan C Dickson  Tra Truong
Abstract:Ectomesenchymal chondromyxoid tumor is a rare neoplasm of uncertain histogenesis that typically occurs in the anterior dorsal tongue. Recent reports in the literature have described rare examples of gingival, palatal and tonsillar lesions. Histologically, ectomesenchymal chondromyxoid tumors are typically well-circumscribed, lacking overtly aggressive features. Herein we report a tumor arising in the right mandible that is morphologically and molecularly consistent with ectomesenchymal chondromyxoid tumor. This case furthers awareness of the extra-glossal distribution of this neoplasm; moreover, it suggests that a subset of these tumors have the potential for locally aggressive behaviour.Electronic supplementary materialThe online version of this article (10.1007/s12105-020-01169-5) contains supplementary material, which is available to authorized users.
Keywords:Ectomesenchymal chondromyxoid tumor  Case report  RREB1  MRTFB  MKL2  Gene rearrangement
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