| MR弥散张量成像在颅内肿瘤病变中的应用 |
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| 引用本文： | 王红,马景旭,贾文霄,王云玲,邓佳敏.MR弥散张量成像在颅内肿瘤病变中的应用[J].中国医学计算机成像杂志,2011,17(4). |
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| 作者姓名： | 王红 马景旭 贾文霄 王云玲 邓佳敏 |
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| 作者单位： | 新疆医科大学第二附属医院影像中心 |
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| 摘 要： | 目的:探讨磁共振弥散张量成像(DTI)FA值和ADC值在颅内肿瘤病变中的应用价值.方法:收集经手术及组织病理学证实胶质瘤患者12例,脑膜瘤10例,神经鞘瘤9例,淋巴瘤8例.术前行常规MRI平扫、增强扫描检查,DTI检查、工作站自动生成各向异性指数图(FA图)及表观弥散系数图(ADC图),分别测量肿瘤实质区的FA值、ADC值,分析比较不同肿瘤之间有无统计学差异.通过扩散张量纤维束示踪(DTT)在肿瘤区和健侧对应部位重建,主要为白质纤维束,并与肿瘤融合,观察纤维束的形态变化.结果:胶质瘤、脑膜瘤、淋巴瘤、神经鞘瘤肿瘤实质区平均FA值为FA1:0.318±0.0036,FA2:0.45±0.052,FA3:0.304±0.012,FA4:0.0362±0.071.ADC值为:ADC1:1.233±0.204,ADC2:1.061±0.039,ADC3:1.014±0.108,ADC4:1.469±0.062.脑膜瘤FA值最高,神经鞘瘤ADC值最高.DTT显示肿瘤与周围脑白质的关系.结论:不同肿瘤的FA值和ADC值存在明显差异,DTT较常规MRI可更好地观察肿瘤造成的白质纤维柬受压移位、浸润与破坏改变.为病变的诊断与鉴别诊断提供更多信息,为手术方案的制定,术后随访提供依据.
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| 关 键 词： | 颅脑肿瘤 DTI FA ADC |
Application of Magnetic Resonance Diffusion Tensor Imaging in Intracranial Tumors |
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| WANG Hong,MA ling-xu,JIA Wen-xiao,WANG Yun-ling,DENG Jia-min.Application of Magnetic Resonance Diffusion Tensor Imaging in Intracranial Tumors[J].Chinese Computed Medical Imaging,2011,17(4). |
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| Authors: | WANG Hong MA ling-xu JIA Wen-xiao WANG Yun-ling DENG Jia-min |
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| Institution: | WANG Hong,MA Jing-xu,JIA Wen-xiao,WANG Yun-ling,DENG Jia-min1 Department of Radiology,Second Affiliated Hospital,Xinjiang Medical UniversityAddress: 38 Nanhu East Rd.,Wulumuqi830063,P.R.C. |
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| Abstract: | Purpose: To disscuss the value of the fractional anisotropy(FA) and apperant diffusion coefficient(ADC) in diagnosing intracranial tumors.Methods: Patients with intracranial tumors which included 12 gliomas,10 meningiomas,9 neurilemmomas,8 lymphomas that were all histology comfirmed underwent the routine and contrast MRI,DTI.FA and ADC values were analyzed before the surgery,the alternation of the fibers via the reconstruction of diffusion tensor tractography(DTT) in tumor area and unaffected side were obse... |
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| Keywords: | Intracranial tumor Diffusion teusor imaging Fractional anistropy Average diffusion coefficient |
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