Time-resolved contrast-enhanced carotid imaging using undersampled projection reconstruction acquisition |
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Authors: | Du Jiang Fain Sean B Korosec Frank R Grist Thomas M Mistretta Charles A |
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Affiliation: | Department of Medical Physics and Radiology, University of Wisconsin, Madison, WI, USA. jiangdu@ucsd.edu |
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Abstract: | PURPOSE: To investigate the utility of nonuniform angular spacing of projections in a three-dimensional (3D) hybrid undersampled projection reconstruction (PR) acquisition for contrast-enhanced (CE) time-resolved carotid imaging. MATERIALS AND METHODS: Carotid CE magnetic resonance angiography (CE-MRA) was performed on seven healthy volunteers using a time-resolved hybrid sequence that combined undersampled PR acquisition in-plane and Cartesian slice encoding through-plane. The undersampling streak artifact comes mainly from the superior-inferior (S/I) direction in carotid imaging and is suppressed by nonuniform distribution of the projections. Phantom and volunteer studies were performed to demonstrate its efficacy. RESULTS: The undersampling streak artifact was significantly suppressed through a nonuniform distribution of the projection angles with more projections aligned along the S/I direction. The hybrid PR sequence combined with nonuniform distribution of the projection angles provided time-resolved images of the carotid arteries with high temporal resolution (two seconds per frame) and high spatial resolution (1.0 x 1.0 x 1.5 mm(3)) simultaneously. CONCLUSION: High-resolution dynamic imaging of the carotid arteries is feasible with the use of a hybrid undersampled PR acquisition. Undersampling streak artifact can be suppressed significantly through nonuniform distribution of the projections. |
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Keywords: | time‐resolved MRI undersampled projection reconstruction carotid artery imaging CE‐MRA non‐uniform distribution |
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