| 肉毒碱对实验性心肌损伤线粒体呼吸酶的影响 |
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| 引用本文： | 宋海燕,曾宪惠.肉毒碱对实验性心肌损伤线粒体呼吸酶的影响[J].哈尔滨医科大学学报,1997,31(1):37-38. |
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| 作者姓名： | 宋海燕 曾宪惠 |
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| 作者单位： | 黑龙江省医院内科 |
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| 摘 要： | 以大剂量维生素Ｄ造成心肌损伤模型，以肉毒碱作为影响因素，通过电镜细胞化学方法，观察了肉毒碱对心肌线粒体细胞色素Ｃ氧化酶和琥珀酸脱氢酶的作用。结果表明，肉毒碱具有提高线粒体呼吸酶活性及保护线粒体膜结构的应用，从而保护了呼吸链的完整性，改善了心肌氧化磷酸化功能。
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| 关 键 词： | 肉毒碱 细胞色素氧化酶 心肌损伤 线粒体呼吸酶 |
Effects of Carnitine on the Activity of Mitochondrial Respiratory Enzyme in Myocardial Damage |
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| Song Haiyan et al.Effects of Carnitine on the Activity of Mitochondrial Respiratory Enzyme in Myocardial Damage[J].Journal of Harbin Medical University,1997,31(1):37-38. |
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| Authors: | Song Haiyan |
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| Institution: | Institute of Keshan Disease |
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| Abstract: | Effects of carnitine on myocardial mitochondrial cytochrome c oxidase (CCO) and succinodehydrogenase(SDH) were observed by the method of electronmicroscopic molecular cytochemistry. The results showed that carnitine could increase the activity of CCO and SDH, and therefore protect the integrality of respiratory chain, improve the function of oxidative phosphorylation. |
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| Keywords: | Carnitine Cytochrome C oxidase Succinodehydrogenase |
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