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| 优化翼状胬肉切除术联合角膜缘干细胞移植术的临床研究 | |
| 引用本文： | 李庆和,胡长娥,李岳美,齐绍文.优化翼状胬肉切除术联合角膜缘干细胞移植术的临床研究[J].国际眼科杂志,2013,13(1):118-120. |
| 作者姓名： | 李庆和 胡长娥 李岳美 齐绍文 |
| 作者单位： | 中国河南省平顶山市,解放军第一五二中心医院眼科;中国河南省平顶山市,解放军第一五二中心医院眼科;中国河南省平顶山市,解放军第一五二中心医院眼科;中国河南省平顶山市,解放军第一五二中心医院眼科 |
| 摘 要： | 目的:研究优化的翼状胬肉切除术联合角膜缘干细胞移植术的临床疗效方法:选择59例59眼初发的翼状胬肉患者,随机分为实验组(优化的翼状胬肉切除术+角膜缘干细胞移植术组)32例32眼和对照组(翼状胬肉切除术+角膜缘干细胞移植术组)27例27眼,分别采用相应的手术方式治疗,比较术后角膜上皮愈合时间、结膜瓣愈合时间、手术操作时间、复发率、术后患者舒适度等并做统计分析。结果:实验组和对照组的术后角膜上皮愈合时间分别为2.16±0.37,2.87±0.31d;手术操作时间分别为30.03±1.98,36.63±2.42min;结膜瓣愈合时间分别为8.06±0.75,10.02±1.01d;术后患者不适感评分分别为0.91±0.69,1.63±0.74。差异均有统计学意义(P<0.01),两组均未见复发病例。结论:采用优化的翼状胬肉切除术联合角膜缘干细胞移植术,术后角膜上皮、结膜瓣愈合时间缩短和手术操作时间明显缩短,术后患者舒适度高。 |
| 关 键 词： | 翼状胬肉 干细胞移植 优化手术 |
| 收稿时间： | 9/6/2012 12:00:00 AM |
| 修稿时间： | 2012/12/11 0:00:00 |
Clinical study of optimizating surgical excision of pterygium and limbal conjunctival transplantation with stem cell |
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| Qing-He Li,Chang-E Hu,Yue-Mei Li and Shao-Wen Qi.Clinical study of optimizating surgical excision of pterygium and limbal conjunctival transplantation with stem cell[J].International Journal of Ophthalmology,2013,13(1):118-120. | |
| Authors: | Qing-He Li Chang-E Hu Yue-Mei Li and Shao-Wen Qi |
| Institution: | Department of Ophthalmology, No.152 Central Hospital of Chinese PLA, Pingdingshan 467000, Henan Province, China;Department of Ophthalmology, No.152 Central Hospital of Chinese PLA, Pingdingshan 467000, Henan Province, China;Department of Ophthalmology, No.152 Central Hospital of Chinese PLA, Pingdingshan 467000, Henan Province, China;Department of Ophthalmology, No.152 Central Hospital of Chinese PLA, Pingdingshan 467000, Henan Province, China |
| Abstract: | AIM: To study clinical effects of optimizating surgical excision of pterygium and limbal conjunctival transplantation with stem cell. METHODS: Primary pterygium patients 59 eyes of 59 cases were selected and randomly divided into two groups. Optimizating surgical excision of pterygium and limbal conjunctival transplantation with stem cell was performed in the experimental group(32 eyes of 32 cases); surgical excision of pterygium and limbal conjunctival transplantation with stem cell was performed in the control group(27 eyes of 27 cases); respectively using the corresponding approach of surgical treatment. The healing time of postoperative corneal epithelial and the conjunctival flap, the time of operative course, the rate of recurrence and postoperative comfort were compared and statistically analyzed. RESULTS: The experimental group and the control group of the healing time of corneal epithelial respectively were 2.16±0.37 and 2.87±0.31 days, the time of operative course were 30.03±1.98 minutes and 36.63±2.42 minutes, the healing time of conjunctival flap were 8.06±0.75 days and 10.02±1.01 days, the scores of postoperative discomfort were 0.91±0.69 and 1.63±0.74. The differences were statistically significant(P<0.01), both groups had no recurrence case. CONCLUSION: Using the optimizating surgical excision of pterygium and limbal conjunctival transplantation with stem cell can shorten the healing time of postoperative corneal epithelial and the conjunctival flap and patient feel more comfort after surgery. |
| Keywords: | pterygium stem cell transplantation optimizated surgery |
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