急诊抢救重症哮喘合并呼吸衰竭的临床效果分析

目的 探讨急诊抢救重症哮喘合并呼吸衰竭的临床效果.方法 将2020年1月—2021年2月在医院急诊科抢救的76例重症哮喘合并呼吸衰竭患者随机分为两组,对照组使用常规药物治疗,在此基础上,观察组使用无创机械通气辅助治疗,对比两组的临床疗效、生命体征变化、肺功能指标变化、炎性因子水平变化、不良反应.结果 观察组治疗有效率为...

Clinical Effect Analysis of Emergency Treatment of Severe Asthma Combined With Respiratory Failure

Objective To investigate the clinical effect of emergency treatment of severe asthma combined with respiratory failure.Methods From January 2020 to February 2021 in our hospital emergency rescue of the combination of respiratory failure,a total of 76 cases of severe asthma patients were randomly divided into two groups,the control group was used conventional drug treatment,on this basis,the observation group was used in the adjuvant treatment of noninvasive mechanical ventilation,compared two groups of clinical curative effect,changes in vital signs,pulmonary function index changes,inflammatory factor levels and adverse reactions.Results The effective rate of the observation group was 94.74%,which was significantly higher than 73.68%of the control group,and the difference was statistically significant(P<0.05).After treatment,RR,HR and PaCO₂ in the observation group were significantly lower than those in the control group,and PaO₂ in the observation group was significantly higher than that in the control group,and the differences were statistically significant(P<0.05),but there was no significant difference in pH between the two groups after treatment(P>0.05).After treatment,the levels of FEV₁,FVC and PEF in the observation group were significantly higher than those in the control group,and the difference was statistically significant(P<0.05);the levels of IL-17,IL-8,MPO and ECP in the observation group after treatment were significantly lower than those in the control group,and the difference was statistically significant(P<0.05);adverse reactions such as dry mouth,flatulence,nausea and vomiting occurred in the observation group compared with the control group,there was no statistically significant difference(P>0.05).Conclusion The clinical effect of emergency treatment of severe asthma complicated with respiratory failure is significant,assisted non-invasive mechanical ventilation can enhance the curative effect,promote the stability of vital signs,improve lung function,reduce the inflammatory response of the body,and contribute to the improvement of prognosis.