复方嗜酸乳杆菌片联合匹维溴铵治疗肠易激综合征患者的临床效果

目的 探究复方嗜酸乳杆菌片联合匹维溴铵治疗肠易激综合征(IBS)患者的临床效果.方法 选取2019年6月至2020年6月我院收诊的150例IBS患者为研究对象,将其随机分为对照组、观察A组、观察B组,各50例.对照组采用匹维溴铵治疗,观察A组采用复方嗜酸乳杆菌片治疗,观察B组采用匹维溴铵联合复方嗜酸乳杆菌片治疗.比较三...

Clinical effect of compound eosinophil-lactobacillus tablets combined with pinaverium bromide in the treatment of patients with irritable bowel syndrome

Objective To explore the clinical effect of compound eosinophil-lactobacillus tablets combined with pinaverium bromide in the treatment of patients with irritable bowel syndrome(IBS).Methods A total of 150 patients with IBS admitted in our hospital from June 2019 to June 2020 were selected as the research objects and randomly divided into control group,observation group A and observation group B,with 50 cases in each group.The control group was treated with piveronium bromide,the observation group A was treated with compound eosinophil-lactobacillus tablets,and the observation group B was treated with piveronium bromide combined with compound eosinophil-lactobacillus tablets.The therapeutic effects of the three groups were compared.Results The total effective rate of treatment in the observation group A and the observation group B was higher than that in the control group,and that in the observation group B was higher than the observation group A,the differences were statistically significant(P<0.05).After treatment,diarrhea and abdominal pain scores in the observation group A and the observation group B were lower than those in the control group,and those in the observation group B were lower than the observation group A,the differences were statistically significant(P<0.05).After treatment,the levels of 5-HT,NPY,CGRP,IL-6 and TNF-α in the observation group A and the observation group B were lower than those in the control group,and those in the observation group B were lower than the observation group A,the differences were statistically significant(P<0.05).There was no significant difference in the total incidence of adverse reactions among three groups(P>0.05).Conclusion Compound eosinophil-lactobacillus tablets combined with piveronium bromide has a significant effect in the treatment of IBS patients,it can significantly improve diarrhea and abdominal pain symptoms,with a high clinical reference and application value,and which is worthy of promotion.