地佐辛与喷他佐辛在结直肠癌手术中的麻醉效果比较 |
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引用本文: | 崔小丽,谢海军,马张鹏,张永斌. 地佐辛与喷他佐辛在结直肠癌手术中的麻醉效果比较[J]. 医学临床研究, 2017, 34(2). DOI: 10.3969/j.issn.1671-7171.2017.02.007 |
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作者姓名: | 崔小丽 谢海军 马张鹏 张永斌 |
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作者单位: | 陕西省榆林市榆阳区人民医院麻醉科,陕西 榆林,719000 |
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摘 要: | [目的] 比较地佐辛和喷他佐辛在结直肠癌手术中的麻醉效果.[方法] 本院行手术治疗的结直肠癌患者90例,随机分为对照组(n=45)和观察组(n=45).对照组采用喷他佐辛麻醉,观察组采用地佐辛麻醉,比较两组麻醉效果及安全性.[结果] 两组麻醉起效时间比较差异无显著性(P>0.05);观察组苏醒时间、定向力恢复时间,短于对照组(P<0.05);观察组丙泊酚用药量少于对照组(P<0.05);两组术前术后12 h视觉模拟评分(VAS)相比较差异无显著性(P>0.05);观察组术后1 h、2 h及4 h VAS评分显著低于对照组(P<0.05);观察组术后并发症发生率8.89%(4/45),低于对照组的17.78%(8/45)(P<0.05).[结论] 结直肠癌根治手术患者采用地佐辛麻醉效果理想,安全性较高,值得推广应用.
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关 键 词: | 镇痛药,阿片类 喷他佐辛/治疗应用 哌啶类/治疗应用 麻醉 |
Application of Opioid Analgesic Drug Docetaxel in Clinical Anesthesia |
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Abstract: | [Objective]To observe the clinical effect of docetaxel, an opioid analgesic, on clinical anesthesia.[Methods]Ninety patients were randomly divided into the control group (n=45) and the observation group (n=45).The control group was treated with pentazocine anesthesia, while the observation group was treated with the opioid analgesic drug docetaxel.The anesthesia effect and safety of the two groups were compared.[Results]There was no significant difference in the onset time of anesthesia between the two groups (P>0.05).The time of awakening and orientation recovery was shorter in the observation group than that in the control group (P<0.05).The dosage of propofol in the observation group was lower than that in the control group (P<0.05).There was no significant difference in the VAS score between the two groups before surgery (P>0.05).In addition, there was no significant difference 12 hours after surgery.The VAS scores at 1 h, 2 h and 4 h post-operation in the observation group were significantly lower than those in the control group (P<0.05).The incidence of postoperative complications in the observation group was 8.89%, which was lower than that in the control group, which was 17.78%.The difference was statistically significant (P<0.05).[Conclusion]The perioperative opioid analgesic effect of docetaxel is ideal and safe.It is worthy of popularization and application. |
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Keywords: | Analgesics Opioid Pentazocine/TU Piperidines/TU Anesthesia |
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