肾功能不全对急性心肌梗死患者住院期间心血管事件发生的影响

目的]探讨肾功能不全对急性心肌梗死(AMI)患者住院期间心血管事件发生的影响.方法]100例AMI住院患者,根据其肾小球滤过率(GFR)不同标准分为肾功能正常组(A组,37例)、轻度肾功能不全组(B组,30例)和中度肾功能不全组(C组,33例).观察比较三组患者的临床特点以及住院期间心血管事件发生情况、病死率及相关危险因素.结果]B、C组与A组相比,患者年龄大、女性患者多、合并高血压、心力衰竭、脑卒中及有脑缺血病史、心功能Killip分级≥Ⅱ级比例明显较高,且差异有显著性(P<0.05);B、C组院内病死率及心血管事件发生率显著高于A组(P<0.05).多因素logistic回归分析发现,肾功能不全是AMI患者出现院内死亡及心血管事件的危险因素.结论]肾功能不全是AMI患者常见的并发症状,其导致患者院内死亡及心血管事件发生的可能性增大,肾功能检测对于AMI患者的临床预后评估具有重要意义.

Correlation between Renal Insufficiency and the Prognosis of Patients with Acute Myocardial Infarction during Hospitalization

Objective] To explore the correlation between renal insufficiency and the prognosis of patients with acute myocardial infarction (AMI) during hospitalization.Methods]One hundred hospitalized patients with AMI were divided into the normal renal function group (A group,n=37), the mild renal insufficiency group (B group, n=30) and the moderate renal insufficiency group (C group,n=33) according to the glomerular filtration rate (GFR).The clinical characteristics, incidence of cardiovascular events during hospitalization, mortality rate and related risk factors were observed.Results]Compared to A group, B group and C group had older patients and more female patients, combined with hypertension, heart failure, stroke or history of cerebral ischemia, and cardiac function Fillip grade ≥ grade Ⅱ;the differences were significantly significant (P<0.05).The mortality rates in the hospital and the incidence rates of cardiovascular events in B group and C group were significantly higher than those in A group (P<0.05).Multivariate logistic regression analysis showed that renal insufficiency was a risk factor for mortality in the hospital and cardiovascular events in patients with AMI.Conclusion]Renal insufficiency is a common complication in patients with AMI, and it can increase mortality in the hospital and the incidence of cardiovascular events.Renal function detection is of great importance in evaluating the clinical outcomes of patients with AMI.