18F-FDG PET/CT显像在评估宫颈癌根治术后转移或复发的价值分析

目的] 分析18F氟脱氧葡萄糖(18F-FDG )正电子发射断层显像术/计算机体层摄影术(PET/ CT)评估宫颈癌根治术后转移或复发的临床价值.方法] 可疑宫颈癌术后复发或转移患者60例,均为宫颈癌根治术术后患者,且有明确病理结果,均进行18F-FDG PET/CT显像检查,与病理及随访结果对照,评定18F-FDG PET/CT在宫颈癌术后转移、复发诊断中的应用价值.结果] ①18F-FDG PET/CT显像检出宫颈癌根治术后转移或复发阳性47例,阴性13例,其中30例肿瘤转移,17例肿瘤局部复发,其诊断灵敏度、特异性、准确性分别为97.83%、85.71%、95.00%,阳性预测值、阴性预测值分别为95.74%、90.31%;②18F-FDG PET/CT与病理及随访检查结果一致性较高(P=0.000).结论] 18F-FDG PET/CT显像对宫颈癌根治术后复发、转移诊断价值高,有其较高的敏感度、特异性、准确性,可为患者的临床治疗提供有效参考.

Value of 18F-FDG PET/CT Imaging in the Evaluation of Metastasis or Recurrence of Cervical Cancer after Radical Operation

Objective]To analyze the clinical value of 18F-deoxyglucose (18F-FDG) positron emission tomography/computed tomography (PET/CT) in evaluating the metastasis or recurrence of cervical cancer after radical operation.Methods]Sixty patients with suspected recurrence or metastasis of cervical cancer after radical operation were studied.All patients had pathological diagnosis of cervical cancer.All underwent 18F-FDG PET/CT examinations and the results were compared with the results of pathology and follow-up.The application value of 18F-FDG PET/CT imaging in the diagnosis of postoperative metastasis and recurrence of cervical cancer was evaluated.Results]18F-FDG PET/CT imaging detected that metastasis or recurrence was positive in 47 cases and negative in 13 cases, 30 cases of which were tumor metastasis and 17 cases which were local recurrence after radical operation of cervical cancer.The diagnostic sensitivity, specificity and accuracy were 97.83%, 85.71% and 95.00%, respectively, and the positive and negative predictive values were 95.74% and 90.31% respectively.The consistency of 18F-FDG PET/CT with results of pathology and follow-up was higher (P=0.000).Conclusion]18F-FDG PET/CT imaging is of high value in the diagnosis of recurrence and metastasis after radical operation of cervical cancer;it has high sensitivity, specificity and accuracy, which can provide effective reference for clinical treatment of cervical cancer.