| 鼻型结外NK/T细胞淋巴瘤PET/CT表现及临床分析 |
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| 引用本文： | 魏立强,王景文,宁丰,崔晶,李鑫,尹秀秀. 鼻型结外NK/T细胞淋巴瘤PET/CT表现及临床分析[J]. 临床血液学杂志, 2011, 0(5) |
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| 作者姓名： | 魏立强 王景文 宁丰 崔晶 李鑫 尹秀秀 |
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| 作者单位： | 首都医科大学附属北京同仁医院血液科; |
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| 摘 要： | 目的:用18F-FDG PET/CT精确揭示鼻型结外NK/T细胞淋巴瘤患者的病灶,探讨病变范围与相关临床指标的关系。方法:22例初诊鼻型结外NK/T细胞淋巴瘤患者治疗前行18F-FDG PET/CT检查,分析鼻、咽部及全身病灶累及范围及播散规律,并分析不同病变范围患者之间ALB、LDH、β2-MG、SUVmax、B症状发生率之间的差异。结果:18F-FDG PET/CT发现每位患者至少有一处病灶,原发病灶在鼻腔、鼻咽、口咽部者分别占81.9%、9.1%、9.1%。病变累及最多的部位为鼻腔(95.5%,21/22)、鼻咽(54.5%,12/22)、左颈部淋巴结(40.9%,9/22)、右颈部淋巴结(40.9%,9/22)、口咽(36.4%,8/22)等。鼻、咽部原发病灶可向邻近部位播散,也可沿淋巴结群依次播散,还可以跳跃方式向远处器官播散。病灶范围较广者组,SUVmax值显著增加,血清β2-MG升高者比例也显著增加。结论:18F-FDG PET/CT能精确发现鼻型结外NK/T细胞淋巴瘤患者鼻、咽部及全身病灶,血清β2-MG水平也能反映病灶的累及范围。
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| 关 键 词： | 鼻型结外NK/T细胞淋巴瘤 PET/CT β2-微球蛋白 |
The analysis of ~(18)F-FDG PET/CT in extranodal nasal type NK/T-cell lymphoma |
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| WEI Liqiang WANG Jingwen NING Feng CUI Jing LI Xin YIN Xiuxiu. The analysis of ~(18)F-FDG PET/CT in extranodal nasal type NK/T-cell lymphoma[J]. Journal of Clinical Hematology, 2011, 0(5) |
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| Authors: | WEI Liqiang WANG Jingwen NING Feng CUI Jing LI Xin YIN Xiuxiu |
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| Affiliation: | WEI Liqiang WANG Jingwen NING Feng CUI Jing LI Xin YIN Xiuxiu(Beijing Tongren Hospital,Capital Medical University,Beijing,100730,China) |
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| Abstract: | Objective:To detect the lesions using 18F-FDG PET/CT in patients with extranodal nature killer/T-cell lymphoma,nasal type and investigate the relationship between disease range and related clinical parameters.Method:Twenty-two diagnosed patients with extranodal NK/T-cell lymphoma in nasal type who received 18F-FDG PET/CT were studied.The lesion with intense F-FDG uptake was defined as the positive and the primary lesion was measured using maximal standard uptake values.The characteristic of lymphoma spreadi... |
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| Keywords: | extranodal NK/T-cell lymphoma nasal type positron emission tomography/computed tomography Beta-2-microglobulin |
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