| 干姜水提物解热镇痛作用的实验研究 |
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| 引用本文： | 马晓茜,赵晓民.干姜水提物解热镇痛作用的实验研究[J].山东医学高等专科学校学报,2011(5):327-329. |
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| 作者姓名： | 马晓茜 赵晓民 |
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| 作者单位： | 山东医学高等专科学校;泰山医学院动脉粥样硬化研究所; |
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| 摘 要： | 目的观察干姜水提物的解热和镇痛作用。方法采用大鼠干酵母致热法,观察干姜水提物的解热作用;应用小鼠醋酸扭体法和小鼠光辐射热甩尾法,观察干姜水提物的镇痛作用。结果干姜水提物低剂量组：随着时间的推移,体温有下降的趋势（F=7.21,P〈0.01）;干姜水提物高剂量组：大鼠在给药后第1小时体温显著降低（P〈0.05）,但给药后第2,3,4小时体温下降不明显（F=1.28,P〉0.05）;吲哚美辛组的大鼠在给药后的第1、2、3、4小时体温均明显降低（F=2.89,P〈0.05）。干姜水提物组明显减少发生醋酸扭体反应的鼠数（P〈0.05）,显著提高小鼠光辐射热甩尾反应的痛阈（P〈0.05）。结论干姜水提物具有解热镇痛作用。
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| 关 键 词： | 干姜水提物 解热 镇痛 |
THE ANTIPYRETIC-ANALGESIC EFFECTS OF AQUEOUS EXTRACT FROM DRIED GINGER |
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| MA Xiao-qian,ZHAO Xiao-min.THE ANTIPYRETIC-ANALGESIC EFFECTS OF AQUEOUS EXTRACT FROM DRIED GINGER[J].Journal of Shandong Medical College,2011(5):327-329. |
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| Authors: | MA Xiao-qian ZHAO Xiao-min |
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| Institution: | MA Xiao-qian,ZHAO Xiao-min(Shandong Medical College,Linyi,China 276000) |
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| Abstract: | Objective To observe the antipyretic-analgesic effects of aqueous extract from dried ginger.Methods The antripyretic effects were observed by the rat febrile models,which were induced by injecting dry yeast subcutaneously.The analgesic effects were observed with acetic acid inducing writhing model and light radiant heat inducing tail-flick latency in mice.Results Compared with the model group,the body temperature of the febrile rats decreased significantly after rats being given aqueous extract from dried g... |
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| Keywords: | Dried ginger aqueous extract Antipyretic Analgesic |
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