| 极低体重早产儿动脉导管未闭的治疗 |
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| 引用本文： | 朱燕林,郭立琳,徐瑞燚,朱文玲,苗齐.极低体重早产儿动脉导管未闭的治疗[J].临床心血管病杂志,2011,27(9). |
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| 作者姓名： | 朱燕林 郭立琳 徐瑞燚 朱文玲 苗齐 |
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| 作者单位： | 1. 北京协和医院心内科,北京,100730
2. 北京协和医院心外科 |
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| 摘 要： | 目的:探讨极低体重早产儿动脉导管未闭(PDA)的治疗方法。方法:本研究回顾性分析6例经外科手术治疗的PDA的极低体重早产儿的临床特点。结果:4例患者布洛芬治疗失败、2例患者因药物禁忌行动脉导管结扎术,术后由对呼吸机依赖转为3～4d过渡脱机,胃肠内喂养耐受性及体重增加显著改善(45±41)∶(258±77)g/周,P<0.001],5例存活患者均无手术并发症,1例患者死于早产儿并发症。结论:对于有手术指征的PDA的极低体重早产儿,外科手术结扎是安全而有效的方法。
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| 关 键 词： | 动脉导管未闭 极低体重 早产儿 手术结扎 |
Therapy of patent ductus arteriosus in very-low-birth-weight premature infants |
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| ZHU Yanlin,GUO Lilin,XU Ruiyi,ZHU Wenling,MIAO Qi.Therapy of patent ductus arteriosus in very-low-birth-weight premature infants[J].Journal of Clinical Cardiology,2011,27(9). |
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| Authors: | ZHU Yanlin GUO Lilin XU Ruiyi ZHU Wenling MIAO Qi |
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| Institution: | ZHU Yanlin1 GUO Lilin1 XU Ruiyi1 ZHU Wenling1 MIAO Qi2 (1Department of Cardiology,2Department of Cardiac Surgery,Peking Union Medical College Hospital,Peking Union Medical College,Chinese Academy of Medical Sciences,Beijing,100730,China) Correspanding author: GUO Lilin,Email: guolilin123@126.com |
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| Abstract: | Objective:To explore the therapy of patent ductus arteriosus(PDA) in very-low-birth-weight premature infants. Method:Clinical features of six very-low-birth-weight premature infants who underwent surgical ligation of PDA were analyzed. Result:Six infants underwent surgical closure of PDA after failure(4/6) of or having contraindications(2/6) to medical treatment.Five infants who were ventilator dependent stopped ventilator use in 3-4 days after operation.Surgical ligation of PDA improved enteral feeding tol... |
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| Keywords: | patent ductus arteriosus prematurity very-low-birth-weight ligation |
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