| 复方苦参注射液联合吉西他滨和顺铂治疗晚期非小细胞肺癌 |
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| 引用本文： | 周海英,胡志雄.复方苦参注射液联合吉西他滨和顺铂治疗晚期非小细胞肺癌[J].中国临床医学,2011,18(4):489-491. |
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| 作者姓名： | 周海英 胡志雄 |
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| 作者单位： | 复旦大学附属金山医院呼吸科,上海,200540 |
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| 摘 要： | 目的：探讨复方苦参注射液联合吉西他滨和顺铂治疗晚期非小细胞肺癌（NSCLC）的临床疗效及其影响。方法：80例晚期NSCLC患者随机分为GP组（吉西他滨加顺铂）和GKP组（吉西他滨加顺铂加复方苦参注射液）。化疗后对患者的疗效及不良反应进行评价。结果：治疗后GP组总有效率为32.5%,GKP组为57.5%（P〈0.05）。GP组1年和2年生存率分别为30.0%和18.0%,GKP组35.0%和20.0%。主要的毒性是3级或4级骨髓抑制,治疗后白细胞、中性粒细胞和血小板的减少率2组之间有显著差异（P〈0.05）。结论：在疗效方面GKP组优于GP组,同时GKP方案的不良反应减少率较GP方案更显著,因此GKP方案值得临床推广使用。
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| 关 键 词： | 非小细胞肺癌 复方苦参注射液 顺铂 吉西他滨 |
Fufang Kushen Zhusheye with Gemcitabine and Cisplatin for Curing of Advanced Non-Small Cell Lung Cancer |
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| ZHOU Haiying,HU Zhixiong.Fufang Kushen Zhusheye with Gemcitabine and Cisplatin for Curing of Advanced Non-Small Cell Lung Cancer[J].Chinese Journal Of Clinical Medicine,2011,18(4):489-491. |
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| Authors: | ZHOU Haiying HU Zhixiong |
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| Institution: | ZHOU Haiying HU Zhixiong Department of Pulmonary Medicine,Jinshan Hospital,Fudan University,Shanghai 200540,China |
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| Abstract: | Objective:To explore the curative effect and other influences of Fufang Kushen Zhusheye combined regimens containing gemcitabine and cisplatin for advanced non-small cell lung cancer(NSCLC).Methods:A total of 80 advanced NSCLC patients were divided randomly into two groups:GP group (gemcitabine,G) plus(cisplatin,P)] and GKP group (GP) plus(Fufang Kushen Zhusheye,K)].The efficacies and side effects were analyzed and compared after chemotherapy.Results: After treatment,the overall response rate was 32.5% in... |
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| Keywords: | Non-small cells lung cancer Fufang kushen zhusheye Cisplatin Gemcitabine |
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