| 血清肿瘤标志物联合检测在肺癌诊断中的价值 |
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| 引用本文： | 张丽. 血清肿瘤标志物联合检测在肺癌诊断中的价值[J]. 山东医学高等专科学校学报, 2011, 0(5): 355-356,359 |
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| 作者姓名： | 张丽 |
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| 作者单位： | 蒙阴县坦埠中心卫生院; |
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| 摘 要： | 目的探讨肿瘤标志物癌胚抗原（CEA）、糖类抗原125（CA125）、神经特异性烯醇化酶（NSE）、细胞角蛋白19片段（CYFRA21-1）检测对肺癌早期诊断的临床价值。方法收集肺癌患者92例和肺良性疾病患者60例,用电化学发光法检测其血清中CEA、CA125、NSE和CYFRA21-1的阳性表达率。结果肺癌组血清肿瘤标志物的阳性率明显高于对照组（P〈0.01）;CEA在肺腺癌中、NSE在小细胞肺癌中、CYFRA21-1在肺鳞癌中的阳性表达率最高（P〈0.01）。四者联合检测可提高阳性率至88.8%,显著高于各单项肿瘤标志物（P〈0.05）。结论肿瘤标志物联合检测可提高肺癌检测的阳性表达率,具有一定的临床应用价值。
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| 关 键 词： | 肿瘤标志物 肺癌 诊断 |
SERUM TUMOR MARKERS IN THE DIAGNOSIS OF LUNG CANCER |
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| ZHANG Li. SERUM TUMOR MARKERS IN THE DIAGNOSIS OF LUNG CANCER[J]. Journal of Shandong Medical College, 2011, 0(5): 355-356,359 |
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| Authors: | ZHANG Li |
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| Affiliation: | ZHANG Li(Tanbu Health Center of Mengyin County,Linyi,China 276214) |
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| Abstract: | Objective To explore the clinical value of carcinoma antigen(CEA) embryo,sugar antigen 125(CA125),nerve specificity enzyme(NSE) and cell keratin footage(19 CYFRA21-1) test in lung cancer diagnosis.Methods The positive expressions of serum CA125,CEA,NSE and CYFRA21-1 in 92 cases of lung cancer and 60 cases of pulmonary benign disease were detected by electrochemiluminescence.Results The positive rates of tumor markers in patients with lung cancer were obviously higher than those of the control group(P<0.01).... |
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| Keywords: | Tumor markers Lung cancer Diagnosis |
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