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小儿先天性心脏病的致病危险因素分析
引用本文:赵跃进,束怀符. 小儿先天性心脏病的致病危险因素分析[J]. 华中科技大学学报(医学版), 1988, 0(Z1)
作者姓名:赵跃进  束怀符
作者单位:山东医科大学卫生系卫生统计学教研室(赵跃进),山东医科大学卫生系卫生统计学教研室(束怀符)
摘    要:本文通过病例-对照调查、单因素分析和双重筛选逐步回归法进行资料处理,探讨了先心病致病危险因素。结果表明,先心病致病的主要危险因素是先心病家族史(相对危险度为11.0),孕期毒物接触(3.63)、孕期精神刺激(5.09)、孕早期感冒(4.13)。其中,室间隔缺损和房间隔缺损主要与前3者有关,法洛四联症主要与孕早期感冒有关。

关 键 词:先天性心脏病  危险因素  逐步回归

A Study on Risk Factors of Congenital Heart Diseasesin Younger Children
Zhao Yuejin,Shu Huaifu. A Study on Risk Factors of Congenital Heart Diseasesin Younger Children[J]. Journal of Huazhong University of Science and Technology(Health Sciences), 1988, 0(Z1)
Authors:Zhao Yuejin  Shu Huaifu
Affiliation:Zhao Yuejin,Shu HuaifuDepartment of Health Statistics,Faculty of Public Health,Jinan Medical University,Jinan
Abstract:A case-control study was made among 153 cases of congenital heart diseases (CHD) and 153 matched controls to investigate the risk factors for CHD in four districts of Jinan (Shandong, China), with single factor analysis and double-screening stepwise regression analysis, four variables were identified as pathogenic risk factors of CHD, including CHD familial history (OR 11.00), toxic chemical exposure during gestation (3.63), mental stress during gestation (5.09) and virus infection (influenza etc.) during early stage of gestation (4.13).
Keywords:congenital heart disease  risk factor  stepwise regression
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