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Immunotropic Effects of Active Immunization with Serotonin-Protein Conjugate in C57Bl/6 Mice Exposed to Immobilization Stress
Authors:T. V. Davydova  V. G. Fomina  L. A. Vetrile  A. M. Fedenko
Affiliation:Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow.
Abstract:Immobilization stress for 14 h induced lymphopenia, hypoplasia of the thymus and spleen, and decrease in functional activity of T lymphocytes and macrophages in C57Bl/6 mice. Active induction of antibodies against serotonin during stress decreased functional activity of T lymphocytes and partially recovered phagocytic activity of peritoneal macrophages.
Keywords:antiserotonin antibodies  stress  lymphocytes  macrophages
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