Immunotropic Effects of Active Immunization with Serotonin-Protein Conjugate in C57Bl/6 Mice Exposed to Immobilization Stress |
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Authors: | T. V. Davydova V. G. Fomina L. A. Vetrile A. M. Fedenko |
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Affiliation: | Institute of General Pathology and Pathophysiology, Russian Academy of Medical Sciences, Moscow. |
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Abstract: | Immobilization stress for 14 h induced lymphopenia, hypoplasia of the thymus and spleen, and decrease in functional activity of T lymphocytes and macrophages in C57Bl/6 mice. Active induction of antibodies against serotonin during stress decreased functional activity of T lymphocytes and partially recovered phagocytic activity of peritoneal macrophages. |
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Keywords: | antiserotonin antibodies stress lymphocytes macrophages |
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