9例正常大小卵巢癌综合征的临床分析

目的：探讨正常大小卵巢癌综合征的临床特点、诊断要点以及处理方案。方法：回顾性分析1990－1996年在我院治疗及病理复核证实的9例正常大小卵巢癌综合征,其中6例为卵巢外腹膜浆液性乳头状腺癌（EPSPC）,2例为卵巢浆液性腺癌,1例为原发灶不明的转移性腺癌。上述9例病人均行肿瘤细胞减灭术,术后均辅以有效多疗程化疗。结果：2例EPSPC分别存活84个月及72个月,随访至1997年12月仍健在。7例已死亡,患者平均生存16．5个月。结论：该综合征治疗上仍首选手术,术后宜辅以有效多疗程化疗。

Clinical analysis of 9 cases of the normal-sized ovary carcinoma syndrome]

OBJECTIVE: To investigate clinical features, diagnostic criteria, treatment methods of a clinically rare "normal-sized ovary carcinoma syndrome". METHODS: Histologic slices of 9 cases of the normal-sized ovary carcinoma syndrome from 1990 to 1996 were retrospectively reviewed. Six of the 9 cases were extraovarian peritoneal serous papillary carcinoma(EPSPC). The other 3 cases were serous adenocarcinoma of the ovary (2 cases) and metastatic adenocarcinoma of unknown origin (1 case). All the patients received optimal cytoreductive surgery combined with multiple courses of effective adjuvant chemotherapy. RESULTS: Two patients with EPSPC survived for 84 months and 72 months respectively up to Dec., 1997. The average survival time of the 7 patients who died of their diseases was 16.5 months. CONCLUSION: For the normal-sized ovary carcinoma syndrome, surgical resection is the first choice of treatment, and postoperative chemotherapy is essential to obtain better prognosis.