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Gene expression signatures in motor neurone disease fibroblasts reveal dysregulation of metabolism,hypoxia‐response and RNA processing functions
Authors:Emily F Goodall  Shelley Kramer  Lize‐Linde Ponger  Paul R. Heath  Marta Milo  Hannah C. Hollinger  Theresa Walsh  J Robin Highley  Simon Olpin  Christopher J. McDermott  Pamela J. Shaw  Janine Kirby
Affiliation:1. Sheffield Institute for Translational Neuroscience (SITraN), Department of Neuroscience, University of Sheffield, Sheffield, UK;2. Department of Biomedical Science, University of Sheffield, Sheffield, UK;3. Metabolic Biochemistry, Sheffield Children's NHS Foundation Trust, Sheffield, UK
Abstract:
Keywords:amyotrophic lateral sclerosis  cell models  fibroblasts  hypoxia response  microarray  microRNA  primary lateral sclerosis
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