The dental implications of chronic use of acidic medicines in medically compromised children |
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Authors: | June H. Nunn Salina K.F. Ng Ian Sharkey Malcolm Coulthard |
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Affiliation: | (1) Department of Child Dental Health, School of Dentistry, Framlington Place, Newcastle upon Tyne, NE2 4BW, UK;(2) Children's Kidney Unit, Royal Victoria Infirmary, Queen Victoria Road, Newcastle upon Tyne, NE1 4LP, UK |
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Abstract: | Objective: Liquid oral medicines form a significant proportion (11%) of the medicines used by the population as a whole, either prescribed or over the counter. The active agent, as well as some of the other ingredients, can pose a threat to oral health. Method: Eight liquid oral medicines and two effervescent preparations routinely prescribed for long term use by paediatric renal patients were assessed for titratable acidity and pH values. Results: All of the medicines tested were acidic and the majority were well below the critical pH of 5.5 at which enamel demineralisation takes place. The titratable acidity values, at a pH of 6.7, ranged between 0.01 and 1.54 for the liquid preparations but were 8.4 and 10.6 for the two effervescent tablets tested. Conclusion: Surplus acid in effervescent preparations while ensuring palatability of medicines and thus compliance, may produce unwanted dental side effects in children who are already medically compromised. |
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Keywords: | Acidic medicines Children Dental health Erosion Medically compromised |
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