| 中药墨旱莲中的三萜皂苷 |
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| 引用本文： | 汤海峰 赵越平 蒋永培 王忠壮 易杨华 雷其云. 中药墨旱莲中的三萜皂苷[J]. 中国药学, 2001, 10(4): 183-186 |
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| 作者姓名： | 汤海峰 赵越平 蒋永培 王忠壮 易杨华 雷其云 |
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| 作者单位： | [1]第四军医大学西京医院药剂科，西安710032 [3]第二军医大学长海医院，上海200433 [4]第二军医大学药学院，上海200433 |
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| 摘 要： | 从中药墨旱莲Eclipta prostrataL．中分离得到5个三萜皂苷，根据理化性质和光谱数据，分别鉴定为eclalbasaponins Ⅱ(1)，Ⅰ(2)，Ⅲ(3)，3-O[β-D-吡喃葡糖(1→2)-β-D-吡喃葡糖]-16R-乙氧基-齐墩果酸-28-O-β-D-吡喃葡糖苷(4)和3-O[β-D-吡喃葡糖(1→2)-β-D-吡喃葡糖]-刺囊酸-28-Oβ-D-吡喃葡糖苷(5)。化合物4和5为新化合物，分别命名为eclalbasaponins XI和eclalbasaponins XII。化合物1和5具有诱导稻瘟霉菌丝变形活性。
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| 关 键 词： | 墨旱莲 三萜皂苷 中药 新化合物 葡糖苷 齐墩果酸 稻瘟霉 菌丝 理化性质 光谱数据 |
Triterpenoid Saponins from Eclipta prostrata L. |
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| Tang Haifeng,Zhao Yueping,Jiang Yongpei,Wang Zhongzhuang,Yi Yanghua,Lei Qiyun. Triterpenoid Saponins from Eclipta prostrata L.[J]. Journal of Chinese Pharmaceutical Sciences, 2001, 10(4): 183-186 |
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| Authors: | Tang Haifeng Zhao Yueping Jiang Yongpei Wang Zhongzhuang Yi Yanghua Lei Qiyun |
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| Abstract: | Five triterpenoid saponins were isolated from the Chinese traditional medicine Eclipta prostrata L.. On the basis of their chemical properties and spectral data, they were identified as eclalbasaponins II(1), I(2), III(3), 3-O-[b-D-glucopyranosyl(12)-b-D-glucopyranosyl]-16a-ethoxy-olean-12-ene-28-oic acid-28-O-b-D-glu-copyranoside(4) and 3-O-[(2-O-sulfuryl-b-D-glucopyranosyl)(12)-b-D-glucopyranosyl]-echinocystic acid-28-O-b-D-glucopyranoside(5). Compounds 4 and 5 are new compounds and named eclalbasaponins XI and XII, respectively. Compounds 1 and 5 induced morphological deformation of Pyricularia oryzae mycelia. |
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| Keywords: | Eclipta prostrata Eclalbasaponin XI Eclalbasaponin XII Pyricularia oryzae Bioassay |
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