| 猪苓汤抗急性药物间质性肾炎的实验研究 |
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| 引用本文： | 许庆友,奚正隆,柴崎敏昭,酒井纪. 猪苓汤抗急性药物间质性肾炎的实验研究[J]. 中国实验方剂学杂志, 1996, 2(6): 15-17 |
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| 作者姓名： | 许庆友 奚正隆 柴崎敏昭 酒井纪 |
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| 作者单位： | 河北省中医药研究所 |
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| 摘 要： | 采用中药猪苓汤对抗庆大霉素所致的急性药物间质性肾炎，取得了减少实验动物ＳＤ大鼠尿Ｎ－乙酰－β－Ｄ－氨基葡萄糖苷酶（ＮＡＧ），降低２４小时尿蛋白，降低血肌酐，提高肌酐清除率的作用，肾脏病理亦有明显改善。
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| 关 键 词： | 猪苓汤，庆大霉素，间质性肾炎 |
| 收稿时间： | 1996-04-23 |
Kidney protected Action of Zhuling Decoction Against Gentamicin-induced Acute Interstitial Nephritis in Rats |
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| XuQingyou,XiZhenglong. Kidney protected Action of Zhuling Decoction Against Gentamicin-induced Acute Interstitial Nephritis in Rats[J]. China Journal of Experimental Traditional Medical Formulae, 1996, 2(6): 15-17 |
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| Authors: | XuQingyou XiZhenglong |
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| Affiliation: | Hebei Institute of Traditional ChineseMedicine,Shijiazhuang,050031 |
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| Abstract: | In the experiment,the antagonism of Zhuling Decoction to gentamicin-induced acute interstitialI nephritis was observed in SD rats. The results showed that the decoction was ableto reduce levels of urinary NAG,24 hour's urinary protein and plasma creatinine,improve creatinine clearance rate,and markedly alleviate nephritic pathologic changes,suggesting that ZhuLing Decoction pronouncedly protected the renal from gentamicin-induced acute nephritic damage. |
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| Keywords: | Zhuling decoction gentamicin interstitial nephritis |
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