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传统急救中成药对L7212小鼠脑膜白血病防治作用的病理观察
引用本文:陈泽涛,李芮,陈刚,张勇,王春海,张宏.传统急救中成药对L7212小鼠脑膜白血病防治作用的病理观察[J].中国实验方剂学杂志,1996,2(4):15-18.
作者姓名:陈泽涛  李芮  陈刚  张勇  王春海  张宏
作者单位:山东中医学院附属医院
基金项目:山东省卫生科技发展基金
摘    要:采用颅内接种白血病细胞造成L_(7212)小鼠脑膜白血病模型,对用药组及对照组脑膜白血病细胞浸润程度进行了病理观察,发现用药各组浸润的程度均较对照组轻,尤以安宫牛黄丸组及清开灵组差异显著,提示该药可试用于临床脑膜白血病的防治。

关 键 词:脑膜白血病,紫雪散,安宫牛黄丸,清开灵注射液,病理

Pathological Study on Preventive and Therapeutic Effects of Chinese Patent Drugs on Meningeal Leukemia in L7212 Mice
Chen Zetao,Li Rui,Chen Gang,Zhang YOng,Wang Chunhai,Zhang Hong.Pathological Study on Preventive and Therapeutic Effects of Chinese Patent Drugs on Meningeal Leukemia in L7212 Mice[J].China Journal of Experimental Traditional Medical Formulae,1996,2(4):15-18.
Authors:Chen Zetao  Li Rui  Chen Gang  Zhang YOng  Wang Chunhai  Zhang Hong
Institution:Internal Medicine Department,Affiliated Hospital of Shandong TCM College,Jinan,250011
Abstract:By intracranial implantation of leukemic cells,an experimental model with meningeal leukemia was set up.Severity of infiltration of the leukemic cells in the meninges was evaluated in the control group and the groups treated with chi-nese patent drugs,The infiItration in the drug-treated groups was found to be milder than that in the control group,and there was significant difference between the group treated withAngong Niuhuang Pill or Qingkailing Injection and the con-trol group,suggesting that these drugs might be used to prevent and treat meningeal leukemia as a clinical trial.
Keywords:Meningeal Leukemia  Zixue Powde  Angong Niuhuang Pill  Qingkailing Injection  Pathology  
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