| 终末期肝病模型对肝硬化失代偿期患者预后的预测价值 |
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| 引用本文： | 郑晓丽,汪良芝,吴宝利. 终末期肝病模型对肝硬化失代偿期患者预后的预测价值[J]. 临床肝胆病杂志, 2011, 27(7): 738-740,745 |
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| 作者姓名： | 郑晓丽 汪良芝 吴宝利 |
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| 作者单位： | 苏州大学附属第三医院消化内科,江苏常州,213003 |
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| 摘 要： | 目的评估终末期肝病模型（MELD）、终末期肝病模型联合Na评分（MELD-Na）、终末期肝病模型评分／血钠比值（MESO指数）、Child-Pugh（CTP）分值对失代偿期肝硬化患者预后的预测价值。方法对140例失代偿期肝硬化患者进行回顾性分析。分别比较3、6及12个月内死亡组和存活组之间的MELD评分、MELD-Na评分、MESO指数及CTP分值，并用受试者工作曲线（ROC）及曲线下面积（AUC）比较MELD、MELD—Na评分、MESO指数和CTP分值判断肝硬化患者预后的准确性并获取最佳临界值。结果在随访的3、6及12个月内死亡组和存活组MELD、MELD—Na、MESO及CTP评分比较有显著差异，在判断患者3、6及12个月生存率的ROC曲线Auc比较中，MELD—Na评分与MESO指数、MELD评分及CTP分值比较具有统计学意义差异（P〈O．05）。而MELD评分与Child-Pugh分值比较差异无统计学意义（P〉0．05）。结论MELD—Na评分、MESO、MELD及CTP均能较好预测肝硬化失代偿期患者预后，其中MELD—Na仍是以上预测失代偿期肝硬化预后中最具优势的评分模型。
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| 关 键 词： | 肝硬化 终末期肝病模型 预后 |
Value of model for end-stage liver disease in prediction of prognosis in patients with decompensated hepatic cirrhosis |
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| ZHENG Xiao-li,WANG Liang-zhi,WU Bao-li. Value of model for end-stage liver disease in prediction of prognosis in patients with decompensated hepatic cirrhosis[J]. Chinese Journal of Clinical Hepatology, 2011, 27(7): 738-740,745 |
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| Authors: | ZHENG Xiao-li WANG Liang-zhi WU Bao-li |
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| Affiliation: | ZHENG Xiao-li,WANG Liang-zhi,WU Bao-li.(Department of Gastroenterology,the Third Affliated Hospital of Suzhou University,Changzhou,Jiangsu 213003,China) |
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| Abstract: | Objective To evaluate the prognostic value of the model for end-stage liver disease(MELD),MELD-Na scoring system(MELD-Na),MELD to serum sodium ratio(MESO) index and Child-Pugh grading for patients with decompensated hepatic cirrhosis.Methods One-hundred and forty decompenstated liver cirrhotic patients were retrospectively analyzed and MELD score,MELD-Na score,MESO index and CTP score was compared between the death and survival groups at 3,6 and 12 months.The accuracy of the four parameters in predeterminin... |
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| Keywords: | liver cirrhosis model for end-stage liver disease prognosis |
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