| 小儿重型肝炎患者外周血T淋巴细胞亚群的变化与临床意义 |
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| 引用本文： | 丁巧云,俞海英,孙薇薇,潘剑,曹兴国,王雷. 小儿重型肝炎患者外周血T淋巴细胞亚群的变化与临床意义[J]. 临床肝胆病杂志, 2011, 27(7): 729-730 |
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| 作者姓名： | 丁巧云 俞海英 孙薇薇 潘剑 曹兴国 王雷 |
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| 作者单位： | 东南大学附属第二医院,南京,210003 |
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| 摘 要： | 目的了解小儿与成人重型肝炎外周血CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量变化的差别，探讨小儿重型肝炎患者外周血T淋巴细胞亚群数量变化与临床意义。方法对35例小儿及30例成人重型肝炎进行外周血CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量检测。结果小儿重型肝炎成活的患儿外周血CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量明显高于死亡组（P〈0．01）：小儿重型肝炎中1岁以内患儿外周血CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量明显高于2～6岁组（P〈0．01）；小儿重型肝炎组CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量明显高于成人重型肝炎组（P〈0．01）；1岁以内的患儿病死率最高（P〈0．05）。结论／JxJL与成人重型肝炎外周血CD3^＋、CD3^＋CD4^＋及CD3^＋CD8^＋T淋巴细胞数量有明显差异，年龄越小，CD3^＋、CD3^＋CD4＋及CD3^＋CD8^＋T淋巴细胞数量越高；dxJL细胞免疫与成人明显不同，年龄越小，病情越重；病死率越高。
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| 关 键 词： | 肝炎 T淋巴细胞亚群 |
The changes of peripheral blood T-lymphocyte subsets in pediatric severe hepatitis |
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| DING Qiao-yun,YU Hai-ying,SUN Wei-wei,et al.. The changes of peripheral blood T-lymphocyte subsets in pediatric severe hepatitis[J]. Chinese Journal of Clinical Hepatology, 2011, 27(7): 729-730 |
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| Authors: | DING Qiao-yun YU Hai-ying SUN Wei-wei et al. |
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| Affiliation: | DING Qiao-yun,YU Hai-ying,SUN Wei-wei,et al.(Affiliated Nanjing Second Hospital of Southeast University,Nanjing 210003,China) |
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| Abstract: | Objective To compare the levels of CD3+,CD3+ CD4+ and CD3+ CD8+ T-lymphocytes in peripheral blood between pediatric and adult patients with severe hepatitis.Methods Peripheral blood from 35 children and 30 adults with severe hepatitis was collected.The levels of peripheral blood CD3+,CD3+ CD4+ and CD3+CD8+ T-lymphocytes were detected by flow cytometry.Results Pediatric group,the first year of children with CD3+,CD3+ CD4+ and CD3+ CD8+ T-lymphocytes was significantly higher than the 2 to 6 years old group(P<... |
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| Keywords: | hepatitis T-lymphocytes subesets |
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