| 盐酸罂粟碱氯化钠注射液细菌内毒素检测法实验研究 |
| |
| 引用本文： | 金卫红,居红枫.盐酸罂粟碱氯化钠注射液细菌内毒素检测法实验研究[J].药学实践杂志,2003,21(6):341-343. |
| |
| 作者姓名： | 金卫红 居红枫 |
| |
| 作者单位： | 江苏省药品检验所,江苏,南京,210008 |
| |
| 摘 要： | 目的：建立盐酸罂粟碱氯化钠注射液的细茵内毒素检查方法。方法：用两个生产厂的鲎试剂对盐酸罂粟碱氯化钠注射液进行干扰试验研究。结果：盐酸罂粟碱氯化钠注射液对细茵内毒素检查无干扰作用。结论：可以用细茵内毒素检查法(凝胶法)代替家兔热原检查法控制其热原。
|
| 关 键 词： | 盐酸罂粟碱氯化钠注射液 细菌内毒素检测法 实验 凝胶法 |
| 文章编号： | 1006-0111(2003)06-0341-03 |
| 收稿时间： | 2003/10/28 0:00:00 |
| 修稿时间： | 2003年10月28 |
Assay for bacteririal endotoxin in papaverine hydrochloride and sodium chloride injection |
| |
| JIN Wei-hong JU Hong-feng.Assay for bacteririal endotoxin in papaverine hydrochloride and sodium chloride injection[J].The Journal of Pharmaceutical Practice,2003,21(6):341-343. |
| |
| Authors: | JIN Wei-hong JU Hong-feng |
| |
| Institution: | Jiangsu Provincial Institution for Drug Control, Nanjing 210008, China;Jiangsu Provincial Institution for Drug Control, Nanjing 210008, China |
| |
| Abstract: | OBJECTIVE: To establish the method of assay for the bacterial endotoxin in papaverine hydrochlo-ride and sodium chloride injection. METHODS: Inhibition and enhancement test was performed with limulus ame-bocyte lysate manufactured by two different companies. RESULTS:The injection will not interfere to the bacterial endotoxins test. CONCLUSIONS: The results suggest that bacterial endotoxins test (gel-clot method) can be used as an replaceable method for the rabbit pyrogen test for papaverine hydrochloride and sodium chloride injection. |
| |
| Keywords: | papaverine hydrochloride and sodium chlorid injection bacterial endotoxin Gel-clot method |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
| 点击此处可从《药学实践杂志》浏览原始摘要信息 |
| 点击此处可从《药学实践杂志》下载免费的PDF全文 |
