Efficacy of mosapride citrate in proximal gastric accommodation and gastrointestinal motility in healthy volunteers: a double-blind placebo-controlled ultrasonographic study |
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| Authors: | Hiroaki Kusunoki Ken Haruma Jiro Hata Tomoari Kamada Manabu Ishii Naohito Yamashita Kazuhiko Inoue Hiroshi Imamura Noriaki Manabe Akiko Shiotani |
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| Affiliation: | (1) Department of General Medicine, Kawasaki Medical School, Matsushima 577, Kurashiki Okayama, 701-0192, Japan;(2) Division of Gastroenterology, Department of Internal Medicine, Kawasaki Medical School, Kurashiki, Japan;(3) Division of Endoscopy and Ultrasound, Department of Clinical Pathology and Laboratory Medicine, Kawasaki Medical School, Kurashiki, Japan |
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| Abstract: | Background Mosapride citrate, a 5-hydroxytryptamine-4 receptor agonist, enhances antral contractions and gastric emptying, but its effects on proximal gastric accommodation and gastroduodenal motility have not been fully studied. The aim of the present study was to clarify the effects of mosapride citrate on proximal gastric accommodation and gastroduodenal motility in healthy volunteers, using ultrasonography. |
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