右美托咪啶辅助改善肺癌根治术麻醉后寒战的临床应用

目的探讨右美托咪啶辅助改善肺癌根治术麻醉后寒战的临床疗效。方法该研究于2010年2月—2012年2月对收治的68例需要进行肺癌根治手术的患者作为研究对象进行了右美托咪啶辅助改善肺癌根治术麻醉后寒战的临床效果研究,并与采用生理盐水的对照组进行临床对比研究。结果两组患者的各一般资料、手术时间、术中输液量及拔管时间比较差异无统计学意义;而研究组的七氟醚用量和曲马多使用率均较对照组明显下降,而阿托品使用率则明显上升,且差异有统计学意义(χ2或t=3.02、12.35、13.47,P<0.05)。研究组患者的术后寒战发生率明显低于对照组,且差异有统计学意义(χ2=14.23,P<0.05)。结论在肺癌根治术后使用右美托咪啶辅助治疗可以有效降低患者麻醉后寒战的发生率。

Incidence of Post-anesthetic Shivering in Patients Undergoing Radical Oper- ation for Lung Cancer Under Dexmedetomidine-amisted Anesthesia

Objective To investigate the incidence of postanesthetic shivering in patients undergoing radical operation for lung cancer under dexmedetomidlne-assisted anesthesia. Methods This study in 2010 February ~2012 year in February 68 cases ad- mitted to the need for lung cancer radical operation of patients as the object of study of dexmedetomidine as an adjunct to improve lung cancer radical operation anesthesia shivering after the study of the clinical effects, and the saline control group clinical com- parative study. Results Two groups of patients with the general information, operation time, intraoperative infusion quantity and ex- tubati0n time comparison showed no significant difference; while the study group of sevoflurane concentration and tramadol use rates were decreased significantly compared with the control group, while atropine use rate increased significantly, and the differ- ence has statistics significance （X2 or t=3.02, 12.35, 13.47, P〈0.05 ）. Research group of patients with postoperative shivering was significantly lower than that of the control group, and the difference was statistically significant （X2=14.23, P〈0.05 ）. Conclusion In radical surgery of lung cancer after use of dexmedetomidine as an adjunct therapy can effectively reduce the incidence of patients after anesthesia shivering.