99m Tc-tetrofosmin SPECT显像在鉴别乳腺包块良恶性病变中的价值

目的 :探讨99mTc tetrofosmin乳腺扫描在鉴别可扪及的乳腺包块良恶性病变中的价值。方法 :采用前瞻性同步盲法。 2 0 0 0年 6月～ 2 0 0 1年 1 2月在我院临床发现乳腺包块的 1 0 1例患者接受SPECT乳腺扫描 ,并与针吸细胞学检察 ,乳腺X片和乳房彩色多谱勒检查进行了对比。全部病例进行了手术 ,以术后病理结果为标准。以四格表进行评价分析。结果 :99mTc tetrofosmin在对可扪及的乳腺包块性质进行鉴别诊断时 ,特异性 84.0 % ,敏感性 86 .3 % ,准确性 85 .1 % ,阳性预测值 84.6 % ,阴性预测值 85 .7%。结论 :99mTc tetrofosmin在对可扪及的乳腺包块进行良恶性质的鉴别时 ,不失为一种方便且较为准确的方法

99mTc - tetrofosmin SPECT for the evaluation of suspicious palpable breast lesions

Purpose:To assess the value of 99m Tc tetrofosmin SPECT in discrimination of malignant from benign breast mass.Methods:The trial was prospective, blind and diagnostic. From 2000.6 to 2001.12, one hundred one consecutive patients with breast mass detected by clinical examination were included. After injection of 740 MBq 99m Tc tetrofosmin intravenously in the arm contralateral to the breast lesion, 99m Tc tetrofosmin SPECT was performed additional to the regular diagnostic procedure. All patients underwent operation within one week. Using histological assessment as a golden standard, we calculated sensitivity, specificity, positive and negative predictive value for 99m Tc tetrofosmin SPECT of the breast mass. Results:The sensitivity for palpable breast lesions was 86 3%, specificity 84.0%, positive and negative predictive value were 84.6% and 85.7% respectively. Conclusions:The results suggested that 99m Tc tetrofosmin SPECT is a valuable tool for the evaluation of palpable breast lesions.