GC-MS法同时测定中药材中29种农药残留量

目的建立一种可同时对29种有机氯、有机磷类农药残留量进行定量检测的方法。方法利用GC-MS技术,配合负化学源检测器,采用选择离子检测法(SIM)进行定量,以石油醚-丙酮混合溶剂为洗脱溶剂,样品通过Florisil硅土柱净化,选择环氧七氯为内标物。结果对48种中药材进行了检测;除敌敌畏、杀虫脒、磷丹及三唑磷外,其余农药的检测限都在0.2～15 g.kg-1之间;以9种中药材为例检测,大部分农药的回收率在70%～120%之间。结论该方法简单、快捷、经济,分析结果达到农残分析的要求,适合大批量样品的同时检测。

Determination of 29 pesticide residues in traditional Chinese medicines by GC-MS

Objective To determine the residues of twenty-nine pesticides including organochlorine,organophosphorus in 48 Chinese medicinal plants.Methods A wide range of screening and quantitative method was established for multiresidue analysis by using gas chromatography-mass spectrometry(GC-MS) with negative chemical ionization(NCI).The samples containing the pollutants were extracted with mixture of petroleun ether-acetone and purified by the florisil columns.Heptachlor epoxide was used as internal standard.Results The detection limit ranged from 0.2-15 μg·kg-1.The recoveries of most pesticides were good with the ranged of 70%-120% in 9 medicine crops.Conclusions This method is rapid,simple,accurate and suitble to determine a great deal of samples simultaneously.