| 经尿道前列腺切除术治疗晚期激素非依赖性前列腺癌可行性分析 |
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| 引用本文： | 杨建勋,付启忠,吕光耀,董胜芳,刘颖.经尿道前列腺切除术治疗晚期激素非依赖性前列腺癌可行性分析[J].中华男科学杂志,2011,17(1):55-58. |
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| 作者姓名： | 杨建勋 付启忠 吕光耀 董胜芳 刘颖 |
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| 作者单位： | 大连大学附属中山医院泌尿外科,辽宁,大连,116001 |
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| 摘 要： | 目的:探讨经尿道前列腺切除术(TURP)在晚期前列腺癌并下尿路症状(LUTS)治疗中的作用。方法:对2004～2009年诊断为晚期前列腺癌合并LUTS的43例患者进行总结,分析TURP术前及术后3、12个月患者的IPSS评分、最大尿流率、以及疾病相关危险因素。结果:术后3个月,非雄激素依赖性前列腺癌患者的IPSS(9.58±0.33)分]、最大尿流率(8.96±0.47)ml/s]与术前(19.60±0.41)分、(4.93±0.68)ml/s]存在显著差异(P<0.05)。随访12个月后IPSS(15.73±0.66)分]、最大尿流率(15.67±0.44)ml/s]与术前相比无显著性差异。多因素分析提示术前表现为急性尿潴留的患者术后预后相对较好,激素非依赖前列腺癌患者预后差。结论:TURP治疗晚期激素非依赖前列腺癌合并LUTS的患者,在短期内可以迅速降低IPSS评分,改善生活质量;远期效果不理想。同时,手术本身也可能带来相关并发症,降低患者生存质量。
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| 关 键 词： | 激素非依赖前列腺癌 下尿路症状 膀胱出口梗阻 经尿道前列腺切除术 |
Transurethral resection of the prostate for advanced hormone-refractory prostate cancer:A feasibility study |
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| YANG Jian-xun,FU Qi-zhong,L Guang-yao,DONG Sheng-fang,LIU Ying.Transurethral resection of the prostate for advanced hormone-refractory prostate cancer:A feasibility study[J].National Journal of Andrology,2011,17(1):55-58. |
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| Authors: | YANG Jian-xun FU Qi-zhong L Guang-yao DONG Sheng-fang LIU Ying |
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| Institution: | YANG Jian-xun,FU Qi-zhong,L(U) Guang-yao,DONG Sheng-fang,LIU Ying |
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| Abstract: | Objective:To investigate the effect of transurethral resection of the prostate(TURP) in the treatment of advanced prostate cancer with bladder outlet obstruction(BOO).Methods:We included in this study 43 cases of advanced prostate cancer with BOO treated by TURP,and analyzed their IPSS,maximum urinary flow rate and relevant risk factors pre-operatively and at 3 and 12 months after TURP.Results:Compared with the baseline,IPSS and the maximum urinary flow rate of the patients showed significant differences 3 ... |
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| Keywords: | hormone-refractory prostate cancer lower urinary tract symptoms bladder outlet obstruction transurethral resection of prostate |
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