盐酸帕罗西汀治疗躯体形式障碍临床研究

目的观察盐酸帕罗西汀治疗躯体形式障碍的临床疗效。方法对75例躯体形式障碍患者给予盐酸帕罗西汀口服治疗,剂量20 mg,每日1次,早餐后服用,疗程4周。于治疗前及治疗4周末采用抑郁自评量表评定临床疗效,并对用药后不良反应进行分析。结果治疗前后抑郁自评量表评分比较差异有统计学意义（P〈0.05）,临床总显效率81.3%,躯体症状较治疗前有显著性改善（P〈0.05）。结论盐酸帕罗西汀治疗躯体形式障碍疗效显著,安全性高,依从性好。

Clinical studies of paroxetine hydrochloride in the treatment of somatoform disorder

Objective To observe clinical effectiveness of paroxetine hydrochloride in the treatment of somatoform disorders.Methods Sevety-five patients with somatoform disorders were theated with paroxetine hydrochloride,20 mg/d orally took after breakfast for 4 weeks.Clinical effectiveness was assessed with the(Self-)rating Depression Scale(SDS) before treatment and at the end of 4th treatment,and the adverse effects were analyzed.Results There was significant difference in the SDS between pre and post-treatment(P<0.05),clinical effectual rate was 81.3%,after treatment,somato-symptoms significantly improved(P<0.05).Conclusion Paroxetine hydrochloride has significant effects,higher safty and better compliance in the treatment of somato-symptoms.