复发性多软骨炎20例临床分析

目的：提高对复发性多软骨炎的认识。方法：收集并分析20例复发性多软骨炎患者的临床和实验室检查资料。结果：发病年龄35－86岁，平均53．4岁，平均病程1．1年。90％的患者均有耳软骨炎；80％有呼吸系统受累，其中75％有鼻软骨炎，4例出现严重的气管、支气管软骨炎；部分患者有关节、皮肤、心脏、血管和神经系统受累；20％合并有其他风湿性疾病或自身免疫病。结论：气管、支气管软骨受累是病情严重的信号。早期诊断，给予激素和免疫抑制剂治疗是改善预后的关键。

Clinical analysis of 20 patients with relapsing polychondritis

Objective To enhance the understanding of relapsing polychondritis (RPC).Method Clinical features,laboratory studies and prognosis of RPC in 20 patients were analyzed.Results The average age at the beginning of disease was 53 4 years (range from 35 to 86).The average course from initiation of clinical symptoms to diagnosis was 1 1 years.Of patients,90% had auricular chondritis,80% had respiratory system involvement,75% had nasal chondritis and 4 patients had severe tracheobronchial chondritis.Involvement in joints,skin,cardiovascular and neurotic system also existed in various frequencies,and 20% of the patients were associated with other rheumatic or autoimmune diseases.Conclusion Extensive laryngo tracheobronchial disease is a vital signal in RPC.Early diagnosis and treatment with corticosteroid and immunosuppressant can improve the prognosis.