肥胖患者体脂分布与血脂、胰岛素抵抗关系探讨

目的 探讨男女肥胖患者体脂分布与血脂、胰岛素抵抗的相关性。方法 将95例肥胖者分为男女两组。两组均空腹测体重、体重指数、腰围、腰臀比、血脂、胰岛素、胰岛素敏感指数。结果 男性肥胖者体重指数、腰臀比均与高密度脂蛋白胆固醇(HDI、HDL1、HDL2)、总甘油三酯、空腹胰岛素水平、胰岛素敏感指数有相关性，而腰臀比与体重指数比较，腰臀比与上述指标关系更明显(P＜0．05)。女性肥胖者体重指数与空腹胰岛素水平、甘油三酯、胰岛素敏感指数有关，腰臀比与空腹胰岛素水平、HDL、HDL2有一定相关性。结论 在男性肥胖中，腰臀比与甘油三酯、高密度脂蛋白胆固醇(HDL、HDLl、HDL2)、胰岛素敏感性有明显关系。

Relationship of fat distribution to serum lipid and insulin resistance of obesity: a preliminary study

Objective To determine the relation of body fat and fat distribution to the serum lipid and insulin resistance of obesity .Methods Ninety five obesity ( excluding the obesity caused by the diabetes?hypertension and heart disease ) were divided into men and women groups. Both groups were measured the weight ?body mass index(BMI)?waistline ?waistline hip ratio(WHR)?serum lipids ?serum insulin and insulin sensibility index . Results Among men , levels of BMI and WHR were correlated with serum all of the cholesterol (HDL?HDL 1?HDL 2)? triglycerides ?insulin and insulin sensibility index,as compared with the WHR and BMI , WHR was significantly relation .( P <0.05) . Among women , BMI was significantly associated with concentrations of insulin ,triglycerides and insulin sensibility index .The WHR was correlated with the serum insulin ?HDL?HDL 2 . Conclusion In men obesity , the WHR was comparably correlated with serum triglycerides?all of the HDL cholesterol and insulin sensibility index .