Current approaches to the diagnosis and treatment of cholangiocarcinoma |
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Authors: | Santosh B Reddy MD Tushar Patel MBChB |
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Institution: | (1) Department of Internal Medicine, Scott and White Memorial Hospital and Clinic, Texas A&M University Health Science Center, 2401 South 31st Street, 76508 Temple, TX, USA |
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Abstract: | Malignancies arising from biliary tract epithelia, or cholangiocarcinoma, are rare tumors that have a poor prognosis. The
incidence of these tumors is gradually increasing in many countries. Recent advances have been made in identifying some of
the risk factors, and the need for appropriate classification is emerging. The diagnosis of cholangiocarcinoma is often difficult
and requires multiple complementary studies. The use of molecular approaches may improve the diagnostic utility of biliary
cytology. Treatment of these tumors is complex, and there are many different treatment options. Although surgical resection
can be curative, many patients with cholangiocarcinoma are diagnosed at an advanced stage when only palliative approaches
can be used. Photodynamic therapy is emerging as a useful modality. |
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