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Influence of perioperative opioid-related patient education: A systematic review and meta-analysis
Institution:1. College of Medicine, King Saud bin Abdulaziz University for health sciences, Jeddah, Saudi Arabia;2. King Abdullah International Medical Research Center, Jeddah, Saudi Arabia;3. Department of Surgery/Orthopedic section, King Abdulaziz Medical City, Jeddah, Saudi Arabia;1. Communication, Culture and Technology Program, The McDonough School of Business, Georgetown University, Washington DC, USA;2. Department of Communication, University of Dayton, Dayton, OH, USA;3. Department of Family Medicine, Georgetown University Medical Center, MedStar Medical Group, Washington DC, USA;4. Communication, Culture and Technology Program, Georgetown University, Washington DC, USA;5. Department of Family Medicine, Georgetown University Medical Center, MedStar Georgetown University Hospital, Washington DC, USA;1. Université Libre de Bruxelles, Faculté des Sciences Psychologiques et de l′Éducation, Brussels, Belgium;2. Institut Jules Bordet, Clinique de Psycho-Oncologie, Université Libre de Bruxelles, Brussels, Belgium;3. Université de Liège, Faculté des Sciences Psychologiques et de l′Éducation, Liège, Belgium;4. Centre de Psycho-Oncologie, Brussels, Belgium;5. Université Catholique de Louvain, Faculté de Médecine, Brussels, Belgium;1. Department of Liberal Arts, Indian Institute of Technology Hyderabad, Hyderabad, India;2. Centre for Medical Psychology & Evidence based, Decision-making, School of Psychology, The University of Sydney, Sydney, New South Wales, Australia;3. Chief Radiation Oncologist, Department of Radiation Oncology, Dr Balabhai Nanavati Hospital, Mumbai, India;1. Institute for Musculoskeletal Health, School of Public Health, Faculty of Medicine and Health, The University of Sydney and Sydney Local Health District, New South Wales, Australia;2. Surgical Outcomes Research Centre, Royal Prince Alfred Hospital, New South Wales, Australia;3. Ingham Institute for Applied Medical Research, South Western Sydney Clinical School, UNSW Sydney, New South Wales, Australia;4. Department of Epidemiology and Preventive Medicine, School of Public Health and Preventive Medicine, Monash University, Victoria, Australia;5. Monash Department of Musculoskeletal Health and Clinical Epidemiology, Cabrini Health, Victoria, Australia;6. Sydney Health Literacy Lab, School of Public Health, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia;7. School of Health Sciences, Faculty of Medicine and Health, The University of Sydney, New South Wales, Australia;8. Institute for Evidence-Based Healthcare, Faculty of Health Sciences and Medicine, Bond University, Queensland, Australia
Abstract:ObjectiveTo determine the role of perioperative protocolized opioid-specific patient education on opioid consumption for individuals undergoing surgical procedures.MethodsWe searched Medline, Embase, and the Cochrane Central Register of Controlled Trials for randomized controlled trials (RCTs) that compared protocolized perioperative opioid-specific patient education to the usual care for adult individuals undergoing surgical interventions. The standardized mean difference (SMD) was used to represent continuous outcomes while the risk ratio (RR) was used to represent dichotomous outcomes.ResultsIn total, 15 RCTs that enrolled 2546 participants were deemed eligible. Protocolized opioid-specific patient education showed a significant reduction in postoperative opioid consumption and postoperative pain score compared to usual care (SMD= –0.15, 95% confidence interval CI]: –0.28 to –0.03 and SMD= –0.17, 95% CI: –0.28 to –0.06, respectively). No significant difference was found between the protocolized opioid-specific patient education and the usual care in terms of the number of refill requests (RR=0.82, 95% CI: 0.50–1.34), patients with opioid leftovers (RR=0.92, 95% CI: 0.78–1.08), and patients taking opioids after hospital discharge.ConclusionsThis meta-analysis demonstrated that protocolized opioid-specific patient education significantly reduces postoperative opioid consumption and pain score but has no influence on the number of opioid refill requests, opioid leftovers, and opioid use after hospital discharge.Practice implicationsHealthcare professionals may offer opioid-related educational sessions for the surgical patients during the perioperative period through a video-based material that emphasizes the role of alternative analgesics to opioids, patients’ expectations about the post-operative pain, and the potential side effects of opioid consumptions.
Keywords:Opioid consumption  Postoperative pain  Patient education  Surgical procedure
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