Management of pelvic sarcoma |
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| Institution: | 1. Department of Surgery, Duke University, Durham, NC, USA;2. Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY, USA;3. Department of Surgery, Memorial Sloan Kettering Cancer Center, New York, NY, USA;1. Key Laboratory of Integrated Oncology and Intelligent Medicine of Zhejiang Province, Department of Hepatobiliary and Pancreatic Surgery, Affiliated Hangzhou First People''s Hospital, Zhejiang University School of Medicine, Hangzhou, 310006, China;2. Westlake Laboratory of Life Sciences and Biomedicine, Hangzhou, 310024, China;3. NHC Key Laboratory of Combined Multi-organ Transplantation, Hangzhou, 310003, China;4. Institute of Organ Transplantation, Zhejiang University, Hangzhou, 310003, China;1. Program in Peritoneal Surface Malignancy, MedStar Washington Hospital Center, Washington, DC, USA;2. Westat, Rockville, MD, USA;1. Department of Colorectal Surgery, The University of Edinburgh, Western General Hospital, Crewe Road South, Edinburgh, EH42XU, UK;2. College of Medicine & Veterinary Medicine, University of Edinburgh, Old Medical School (Anatomy), Teviot Place, Edinburgh, EH8 9AG, UK;3. Department of Colorectal Surgery, Manchester Royal Infirmary, Oxford Road, Manchester, M13 9WL, UK;1. Division of Cancer Surgery, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia;2. Division of Radiation Oncology, Peter MacCallum Cancer Centre, Melbourne, Victoria, Australia;3. Sir Peter MacCallum Department of Oncology, University of Melbourne, Parkville, Victoria, Australia;4. Central Clinical School, Alfred Hospital, Monash University, Melbourne, Victoria, Australia;5. Department of Surgical Oncology, University of Texas MD Anderson Cancer Center, Houston, TX, USA;6. Department of Health Services Research, The University of Texas MD Anderson Cancer Center, Houston, TX, USA |
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| Abstract: | Pelvic sarcomas are a rare and heterogenous group of tumors divided into two groups: soft tissue sarcomas and bone sarcomas. Soft tissue sarcomas of the pelvis include most commonly liposarcoma, leiomyosarcoma, gastrointestinal stromal tumors, malignant peripheral nerve sheath tumors, and solitary fibrous tumors. Bone sarcomas of the pelvis most commonly include osteosarcoma and chondrosarcoma. Multidisciplinary treatment at a center experienced in the treatment of sarcoma is essential. Management is dictated by histologic type and grade. Surgical resection with wide margins is the cornerstone of treatment for pelvic sarcomas, although this is often challenging due to anatomic constraints of the pelvis. Multimodal treatment is critical due to the high risk of local recurrence in the pelvis. |
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