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Editorial Commentary: Soaking Anterior Cruciate Ligament Grafts in Vancomycin Solution Lowers Infection Rates Without Lowering Functional Outcomes
Affiliation:1. Department of Orthopaedic Surgery, Naval Medical Center San Diego, San Diego, California, U.S.A.;2. University of Iowa Sports Medicine, Iowa City, Iowa, U.S.A.;3. Mayo Clinic Arizona, Phoenix, Arizona, U.S.A.;4. University of Wisconsin Health at the American Center, Madison, Wisconsin, U.S.A.;5. Department of Orthopaedic Surgery, Wake Forest School of Medicine, Winston-Salem, North Carolina, U.S.A.;6. AZBSC Orthopedics, Scottsdale, Arizona, U.S.A.;7. ProOrtho Surgeons
Abstract:Soaking anterior cruciate ligament grafts in vancomycin solution is done by many surgeons. Research has indicated decreased infection rates and similar anterior cruciate ligament retear rates between grafts soaked in vancomycin solution before implantation versus those without. In addition, there has been basic science evidence for tenocyte survival and viability even when exposed to vancomycin solution. The next frontier, investigating the maturation of vancomycin-soaked grafts with advanced imaging, may cause some surgeons to reconsider the practice but should not stop it, based on the available literature.
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