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广东地区妇女乳腺癌高危因素分析与对策
引用本文:张安秦,夏建红,王颀,李文萍,许娟,陈中扬,杨剑敏.广东地区妇女乳腺癌高危因素分析与对策[J].南方医科大学学报,2009,29(7):1451.
作者姓名:张安秦  夏建红  王颀  李文萍  许娟  陈中扬  杨剑敏
作者单位:广东省妇幼保健院乳腺病防治中心,广东,广州,510010
摘    要:目的 分析广东地区妇女乳腺癌的危险因素,为建立乳腺癌风险模型,有针对性地筛查高危人群进行早期干预提供依据.方法 采用成组配对的病例对照研究,对绝经前和绝经后妇女分别进行乳腺癌人群和非乳腺癌人群危险因素的单因素分析和Logistic多元回归分析.结果 绝经前妇女中,服用避孕药、亲属中有乳腺癌患者、有不良情绪、有不良事件、劳动强度大等因素是乳腺癌的危险因素;有乳腺增生病史、有乳腺组织活检史、有相对剧烈的运动等因素可能是乳腺癌的保护因素.绝经后妇女中,亲属中有乳腺癌患者是危险因素,情绪调节能力强是保护因素.结论 绝经前后乳腺癌的危险因素和保护因素不完全相同,根据不同的影响因素,建立绝经前后不同的乳腺癌预报模型,更有针对性地进行乳腺癌的早期干预应是今后工作的重点.
Abstract:
Objective To screen high-risk population of breast cancer by analyzing the risk factors of breast cancer in Guangdong Province.Methods A case-control study was performed to identify the risk factors of breast cancer between premenopausal women and postmenopausal women. Chi-square test and unconditional logistic regression were used to analyze the data. Results In premenopansal women,prophylactic, family history of breast cancer, bad mood, bad life incidence and work load were the risk factors,and breast hyperplasia history,breast tissue examination history,regular exercise and sleeping without bm were the protective factors.In postmenopausal women,family history of breast cancer was the risk factor, and breast hyperplasia history and mood adjustment were the protective factors. Conclusion The risk and protective factors of breast cancer differ between premenopausal and postmenopausal women,which highlights the importance of using different risk models to screen the high-risk populations.

关 键 词:乳腺肿瘤  危险因素  绝经前  绝经后  预防策略  广东

Risk factors of breast cancer in women in Guangdong and the countermeasures
ZHANG An-qin,XIA Jian-hong,WANG Qi,LI Wen-ping,XU Juan,CHEN Zhong-yang,YANG Jian-min.Risk factors of breast cancer in women in Guangdong and the countermeasures[J].Journal of Southern Medical University,2009,29(7):1451.
Authors:ZHANG An-qin  XIA Jian-hong  WANG Qi  LI Wen-ping  XU Juan  CHEN Zhong-yang  YANG Jian-min
Institution:ZHANG An-qin,XIA Jian-hong,WANG Qi,LI Wen-ping,XU Juan,CHEN Zhong-yang,YANG Jian-min Guangdong Women and Children Hospital,Guangzhou 510010,China
Abstract:Objective To screen high-risk population of breast cancer by analyzing the risk factors of breast cancer in Guangdong Province.Methods A case-control study was performed to identify the risk factors of breast cancer between premenopausal women and postmenopausal women.Chi-square test and unconditional logistic regression were used to analyze the data.Results In premenopausal women,prophylactic,family history of breast cancer,bad mood,bad life incidence and work load were the risk factors,and breast hyperpla...
Keywords:breast neoplasms  risk factors  premenopausal  postmenopausal  strategy  Guangdong Province  
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