胰腺和肝脏在联合移植时互惠作用的观察

作者对观察肝脏对胰腺的免疫保护作用和胰腺对肝脏的营养保护作用,采用大鼠单独胰腺移植,单独肝脏移植及肝胰联合移植进行研究。结果显示;胰腺联合肝脏移植时,胰腺平均功能存活期较单独移植时显著延长,间质排斥反应减轻,分级分布与单独移植相比差异有显著性意义;肝脏有联合移植时,术后再生能力以及形态的完整性估于单独移植。

The mutual benefit role of pancreas and liver in combined transplantation

We study observed the mutual benefits of pancreas and liver in combined hepaticopancreatic transplantation in rats. The result indicated that pancreas, when transplanted with liver, could survive for a significantly longer time (13.4 +/- 1.01 days) than it transplanted alone (9.2 +/- 1.14 days) (P < 0.05). The interstitial rejection was mild and its rejection grade was significantly different from that of pancreas transplanted alone (P < 0.05, chi 2 test). The liver, when transplanted with pancreas, regenerated with strong competence and contact structure morphologically compared with liver transplanted alone. We concluded that pancreas could be immunologically protected against rejection and liver can be nutritionalized by pancreas in combined pancreas and liver transplantation.