| 肾移植受者外周血中人疱疹病毒6型 |
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| 引用本文： | 杨勇,臧美孚.肾移植受者外周血中人疱疹病毒6型[J].中华外科杂志,1997,35(8):499-500,I071. |
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| 作者姓名： | 杨勇 臧美孚 |
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| 作者单位： | 解放军总医院泌尿外科，中国医学科学院中国协和医科大学北京协和医院泌尿外科 |
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| 摘 要： | 为了检测人疱疹病毒６型（ＨＨＶ－６）在器官移植中的致病性甲状作者对１２例肾脏移植受者在经基础免疫治疗３周后，取外周血淋巴细胞与脐血淋巴细胞共同培养。结果显示，２例受示标本中见有细胞病变（ＣＰＥ），其中１株病毒经多次传代冻存后仍能产生ＣＰＥ。该杂细胞超薄切片电镜下风疱疹病毒样颗粒，感染细胞涂片抗ＨＨＶ－６单克隆抗体产生明显荧光，证实为ＨＨＶ－６。作者认为，ＨＨＶ－６可能在肾脏移植后感染，尤其在排斥反
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| 关 键 词： | 人疱疹病毒6型 肾移植 移植物排斥 |
Isolation of human herpes virus 6 from preipheral blood of renal transplant recipients |
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| Yang Yong,Zang Myfu,Meng Shuli.Isolation of human herpes virus 6 from preipheral blood of renal transplant recipients[J].Chinese Journal of Surgery,1997,35(8):499-500,I071. |
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| Authors: | Yang Yong Zang Myfu Meng Shuli |
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| Institution: | Yang Yong,Zang Myfu,Meng Shuli. Department of Urology,People's Liberation Army General Hospital,Beijing 100853. |
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| Abstract: | One strain of the viruses was isolated from preipheral blood lymphocytes(PBL) of a renal transplant recipient.PBL isolated from blood samples were cocultured with the PHA actived cord blood lymphocytes(CBL).Two of twelve recipient's samples found cytopathic effect after 10 to 14 days. Examination of ultrathin sections of the virus infected cells by electron microscope showed herpes like virus particles.Detection of indirect immunofluorescences with McAbs against HHV 6 was positive in the infected cells. |
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| Keywords: | Human herpes virus 6 Kidney transplantation Graft rejection |
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