Effects of Loading Orientation on the Morphology of the Predicted Yielded Regions in Trabecular Bone |
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Authors: | Xiutao Shi Xiang Wang and Glen L Niebur |
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Institution: | (1) Tissue Mechanics Laboratory, Department of Aerospace and Mechanical Engineering, University of Notre Dame, Notre Dame, IN 46556, USA |
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Abstract: | While the effects of bone mineral density and architecture in osteoporotic bone have been studied extensively, the micromechanics
of yielding and failure have received less attention. However, understanding architectural features associated with failure
should provide insight into assessing bone quality. In this study, microstructural finite element models were used to compute
regions of tissue level yielding in ten bovine tibial trabecular bone samples. The morphology, number, and mean volume of
the yielded regions were quantified for four apparent strains under two loading conditions. For on-axis loading, the mean
aspect ratio of the tissue that yielded due to compressive strain increased with increasing apparent strain, expanding along
the principal trabecular orientation. This suggests that tissue level yielding progresses along vertical trabeculae when a
specimen is loaded on-axis. The number, but not the volume, of the regions yielded due to tensile strain increased with increasing
applied load, consistent with relaxation and redistribution of stresses around the yielded regions. When the specimens were
compressed perpendicular to the principal axis, the aspect ratio of the yielded regions was close to one, while the number,
mean volume, and mean thickness of the yielded regions increased. This indicates that localized high strains consistent with
bending rather than axial deformation of struts occur at the tissue level. Overall, the results provide new insight into trabecular
bone failure, which is relevant to assessing diagnostic tests for fracture risk or evaluating osteoporosis treatments. |
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Keywords: | Trabecular bone Architecture Finite element analysis Morphology |
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