PAPULAR MUCINOSIS (SCLEROMYXOEDEMA) COMPLICATING DIFFUSE SYSTEMIC SCLEROSIS: CLINICAL FEATURES AND ELECTRON MICROSCOPE OBSERVATIONS期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

PAPULAR MUCINOSIS (SCLEROMYXOEDEMA) COMPLICATING DIFFUSE SYSTEMIC SCLEROSIS: CLINICAL FEATURES AND ELECTRON MICROSCOPE OBSERVATIONS

Authors:	VARGA, J. MATSUOKA, L. Y. HASHIMOTO, K. LEONARDO, M. DI JIMENEZ, S. A.

Affiliation:	^*Departments of Medicine $"{dagger}"$ Dermatology, Jefferson Medical College, Thomas Jefferson University Philadelphia, PA, USA $"{ddagger}"$ Department of Dermatology, Wayne State University Detroit, MI, USA

Abstract:	Papular mucinosis (scleromyxoedema) is an uncommon disordercharacterized by generalized papular eruption and cuta neousinduration, which may be associated with a variety of extracutaneousmanifestations. Although scleroderma and papular mucinosis sharemany features, they are clinically and histologically distinctentities. We report here a patient with diffuse sclerodermawho developed superimposed papular mucinosis. Degranulatingmast cells were a prominent ultra- structural finding in theinvolved skin. The occurrence of scleroderma and papular mucinosis,two uncommon cutaneous indurative diseases, in the same patienthas not been described previously. KEY WORDS: Papular mucinosis, Scleromyxoedema, Systemic sclerosis, Cutaneous mucinosis

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